Gene Expression Profiling of Gliadin Effects on Intestinal Epithelial Cells Suggests Novel Non-Enzymatic Functions of Pepsin and Trypsin

Gliadin triggers T-cell mediated immunity in celiac disease, and has cytotoxic effects on enterocytes mediated through obscure mechanisms. In addition, gliadin transport mechanisms, potential cell surface receptors and gliadin-activated downstream signaling pathways are not completely understood. In...

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Detalles Bibliográficos
Autores principales: Parmar, Amarjit, Greco, Dario, Venäläinen, Jarkko, Gentile, Massimiliano, Dukes, Emma, Saavalainen, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688875/
https://www.ncbi.nlm.nih.gov/pubmed/23824913
http://dx.doi.org/10.1371/journal.pone.0066307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688875/
https://www.ncbi.nlm.nih.gov/pubmed/23824913
http://dx.doi.org/10.1371/journal.pone.0066307

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