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Gene Expression Profiling of Gliadin Effects on Intestinal Epithelial Cells Suggests Novel Non-Enzymatic Functions of Pepsin and Trypsin
Gliadin triggers T-cell mediated immunity in celiac disease, and has cytotoxic effects on enterocytes mediated through obscure mechanisms. In addition, gliadin transport mechanisms, potential cell surface receptors and gliadin-activated downstream signaling pathways are not completely understood. In...
Autores principales: | Parmar, Amarjit, Greco, Dario, Venäläinen, Jarkko, Gentile, Massimiliano, Dukes, Emma, Saavalainen, Päivi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688875/ https://www.ncbi.nlm.nih.gov/pubmed/23824913 http://dx.doi.org/10.1371/journal.pone.0066307 |
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