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Genome-Wide Association Study of Genetic Variants in LPS-Stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α Cytokine Response in a Danish Cohort

BACKGROUND: Cytokine response plays a vital role in various human lipopolysaccharide (LPS) infectious and inflammatory diseases. This study aimed to find genetic variants that might affect the levels of LPS-induced interleukin (IL)-6, IL-8, IL-10, IL-1ra and tumor necrosis factor (TNF)-α cytokine pr...

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Detalles Bibliográficos
Autores principales:	Larsen, Margit Hørup, Albrechtsen, Anders, Thørner, Lise Wegner, Werge, Thomas, Hansen, Thomas, Gether, Ulrik, Haastrup, Eva, Ullum, Henrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688878/ https://www.ncbi.nlm.nih.gov/pubmed/23823136 http://dx.doi.org/10.1371/journal.pone.0066262

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