CCL20 Secretion from the Nucleus Pulposus Improves the Recruitment of CCR6-Expressing Th17 Cells to Degenerated IVD Tissues

BACKGROUND: Studies elucidated that Th17 cells are important contributors to the pathogenesis of many immune-mediated diseases, and IL-17A is present in pathologic intervertebral disc (IVD) tissues. However, the mechanisms, how these cells traffic into the degenerate discs are not clear. MATERIALS A...

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Detalles Bibliográficos
Autores principales: Zhang, Wen, Nie, Lin, Wang, Yan, Wang, Xu-ping, Zhao, Hua, Dongol, Samina, Maharjan, Sailendra, Cheng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688882/
https://www.ncbi.nlm.nih.gov/pubmed/23823618
http://dx.doi.org/10.1371/journal.pone.0066286

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