Cargando…

Quantitative Segmentation of Fluorescence Microscopy Images of Heterogeneous Tissue: Application to the Detection of Residual Disease in Tumor Margins

PURPOSE: To develop a robust tool for quantitative in situ pathology that allows visualization of heterogeneous tissue morphology and segmentation and quantification of image features. MATERIALS AND METHODS: Tissue excised from a genetically engineered mouse model of sarcoma was imaged using a subce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mueller, Jenna L., Harmany, Zachary T., Mito, Jeffrey K., Kennedy, Stephanie A., Kim, Yongbaek, Dodd, Leslie, Geradts, Joseph, Kirsch, David G., Willett, Rebecca M., Brown, J. Quincy, Ramanujam, Nimmi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688889/ https://www.ncbi.nlm.nih.gov/pubmed/23824589 http://dx.doi.org/10.1371/journal.pone.0066198

Ejemplares similares

Optical breast cancer margin assessment: an observational study of the effects of tissue heterogeneity on optical contrast
por: Kennedy, Stephanie, et al.
Publicado: (2010)

Structured Illumination Microscopy and a Quantitative Image Analysis for the Detection of Positive Margins in a Pre-Clinical Genetically Engineered Mouse Model of Sarcoma
por: Fu, Henry L., et al.
Publicado: (2016)

Optimization of a Widefield Structured Illumination Microscope for Non-Destructive Assessment and Quantification of Nuclear Features in Tumor Margins of a Primary Mouse Model of Sarcoma
por: Fu, Henry L., et al.
Publicado: (2013)

Optical Spectral Surveillance of Breast Tissue Landscapes for Detection of Residual Disease in Breast Tumor Margins
por: Brown, J. Quincy, et al.
Publicado: (2013)

Advancing Optical Imaging for Breast Margin Assessment: An Analysis of Excisional Time, Cautery, and Patent Blue Dye on Underlying Sources of Contrast
por: Bydlon, Torre M., et al.
Publicado: (2012)

Performance metrics of an optical spectral imaging system for intra-operative assessment of breast tumor margins
por: Bydlon, Torre M., et al.
Publicado: (2010)

A Fluorescence-Guided Laser Ablation System for Removal of Residual Cancer in a Mouse Model of Soft Tissue Sarcoma
por: Lazarides, Alexander L., et al.
Publicado: (2016)

Efficacy of Phosphatidylinositol-3 Kinase Inhibitors in a Primary Mouse Model of Undifferentiated Pleomorphic Sarcoma
por: Kim, Suzy, et al.
Publicado: (2012)

Locoregional Thermal and Chemical Tumor Ablation: Review of Clinical Applications and Potential Opportunities for Use in Low- and Middle-Income Countries
por: Quang, Tri T., et al.
Publicado: (2023)

Intraoperative detection and removal of microscopic residual sarcoma using wide-field imaging
por: Mito, Jeffrey K, et al.
Publicado: (2012)

Wavelength Optimization for Quantitative Spectral Imaging of Breast Tumor Margins
por: Lo, Justin Y., et al.
Publicado: (2013)

Rapid assessment of breast tumor margins using deep ultraviolet fluorescence scanning microscopy
por: Lu, Tongtong, et al.
Publicado: (2020)

Microscopy with ultraviolet surface excitation for rapid slide-free histology
por: Fereidouni, Farzad, et al.
Publicado: (2017)

Delivery-Corrected Imaging of Fluorescently-Labeled Glucose Reveals Distinct Metabolic Phenotypes in Murine Breast Cancer
por: Frees, Amy E., et al.
Publicado: (2014)

Rapid diagnosis and intraoperative margin assessment of human lung cancer with fluorescence lifetime imaging microscopy
por: Wang, Mengyan, et al.
Publicado: (2017)

In Vivo Evaluation of Safety and Efficacy of Ethyl Cellulose-Ethanol Tissue Ablation in a Swine Cervix Model
por: Quang, Tri T., et al.
Publicado: (2023)

A Quantitative Diffuse Reflectance Imaging (QDRI) System for Comprehensive Surveillance of the Morphological Landscape in Breast Tumor Margins
por: Nichols, Brandon S., et al.
Publicado: (2015)

Accuracy of Ex-vivo Fluorescence Confocal Microscopy in Margin Assessment of Solid Tumors: A Systematic Review
por: Au, Matthew, et al.
Publicado: (2023)

An integrated strategy for improving contrast, durability, and portability of a Pocket Colposcope for cervical cancer screening and diagnosis
por: Lam, Christopher T., et al.
Publicado: (2018)

Heterogeneous architecture of vertebrate kinetochores revealed by three-dimensional superresolution fluorescence microscopy
por: Wynne, David J., et al.
Publicado: (2016)

Near-simultaneous intravital microscopy of glucose uptake and mitochondrial membrane potential, key endpoints that reflect major metabolic axes in cancer
por: Zhu, Caigang, et al.
Publicado: (2017)

Fluorescence microscopy
por: Herman, Brian
Publicado: (1998)

Digital imaging fluorescence microscopy: spatial heterogeneity of photobleaching rate constants in individual cells
Publicado: (1985)

Modality Attention and Sampling Enables Deep Learning with Heterogeneous Marker Combinations in Fluorescence Microscopy
por: Gomariz, Alvaro, et al.
Publicado: (2021)

Super-multiplex imaging of cellular dynamics and heterogeneity by integrated stimulated Raman and fluorescence microscopy
por: Shou, Jingwen, et al.
Publicado: (2021)

Bridging fluorescence microscopy and electron microscopy
por: Giepmans, Ben N. G.
Publicado: (2008)

Intraoperative Digital Analysis of Ablation Margins (DAAM) by Fluorescent Confocal Microscopy to Improve Partial Prostate Gland Cryoablation Outcomes
por: Selvaggio, Oscar, et al.
Publicado: (2021)

Optimizing ethyl cellulose-ethanol delivery towards enabling ablation of cervical dysplasia
por: Mueller, Jenna L., et al.
Publicado: (2021)

Spatiotemporal Heterogeneity of κ-Carrageenan Gels Investigated via Single-Particle-Tracking Fluorescence Microscopy
por: Martens, Koen J. A., et al.
Publicado: (2020)

High-Throughput Time-Lapse Fluorescence Microscopy Screening for Heterogeneously Expressed Genes in Bacillus subtilis
por: Mortier, Julien, et al.
Publicado: (2022)

Gigapixel surface imaging of radical prostatectomy specimens for comprehensive detection of cancer-positive surgical margins using structured illumination microscopy
por: Wang, Mei, et al.
Publicado: (2016)

Quantitative Fluorescence Microscopy on SARS-CoV-2
por: Addabbo, Rayna M., et al.
Publicado: (2021)

Rationalizing Inter- and Intracrystal Heterogeneities in Dealuminated Acid Mordenite Zeolites by Stimulated Raman Scattering Microscopy Correlated with Super-resolution Fluorescence Microscopy
por: Liu, Kuan-Lin, et al.
Publicado: (2014)

Highly heterogeneous residual malaria risk in western Thailand
por: Nguitragool, Wang, et al.
Publicado: (2019)

Fluorescence Microscopy in Exfoliative Cytology
por: Grubb, C., et al.
Publicado: (1961)

Inducible fluorescent speckle microscopy
por: Pereira, António J., et al.
Publicado: (2016)

Combining fluorescence and bioluminescence microscopy
por: Goda, Kazuhito, et al.
Publicado: (2015)

Advanced Methods in Fluorescence Microscopy
por: Fritzky, Luke, et al.
Publicado: (2013)

Ångström-resolution fluorescence microscopy
por: Reinhardt, Susanne C. M., et al.
Publicado: (2023)

Recent Advances in Fluorescent Labeling Techniques for Fluorescence Microscopy
por: Suzuki, Takeshi, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_ts427lnt9itau0evuaatqg2d4n