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The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility
Persistent cellular migration requires efficient protrusion of the front of the cell, the leading edge where the actin cytoskeleton and cell-substrate adhesions undergo constant rearrangement. Rho family GTPases are essential regulators of the actin cytoskeleton and cell adhesion dynamics. Here, we...
Autores principales: | Mitin, Natalia, Rossman, Kent L., Currin, Rachel, Anne, Sandeep, Marshall, Thomas W., Bear, James E., Bautch, Victoria L., Der, Channing J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688894/ https://www.ncbi.nlm.nih.gov/pubmed/23825001 http://dx.doi.org/10.1371/journal.pone.0066260 |
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