Bee Venom Phospholipase A2, a Good “Chauffeur” for Delivering Tumor Antigen to the MHC I and MHC II Peptide-Loading Compartments of the Dendritic Cells: The Case of NY-ESO-1

Bee venom phospholipase A2 (bvPLA2) is a small, 15kDa enzyme which hydrolyses many phospholipids through interfacial binding. The mutated bvPLA2H34Q (bvPLA2m), in which histidine-34 is replaced by glutamine, is not catalytically active. This protein has been shown to be a suitable membrane anchor an...

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Detalles Bibliográficos
Autores principales: Almunia, Christine, Bretaudeau, Marie, Held, Gerhard, Babon, Aurélie, Marchetti, Charles, Castelli, Florence Anne, Ménez, André, Maillere, Bernard, Gillet, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688974/
https://www.ncbi.nlm.nih.gov/pubmed/23825678
http://dx.doi.org/10.1371/journal.pone.0067645

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