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Sox2 Level Is a Determinant of Cellular Reprogramming Potential

Epiblast stem cells (EpiSCs) and embryonic stem cells (ESCs) differ in their in vivo differentiation potential. While ESCs form teratomas and efficiently contribute to the development of chimeras, EpiSCs form teratomas but very rarely chimeras. In contrast to their differentiation potential, the rep...

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Detalles Bibliográficos
Autores principales: Han, Dong Wook, Tapia, Natalia, Araúzo-Bravo, Marcos J., Lim, Kyung Tae, Kim, Kee Pyo, Ko, Kinarm, Lee, Hoon Taek, Schöler, Hans R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688988/
https://www.ncbi.nlm.nih.gov/pubmed/23825671
http://dx.doi.org/10.1371/journal.pone.0067594

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