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Sox2 Level Is a Determinant of Cellular Reprogramming Potential
Epiblast stem cells (EpiSCs) and embryonic stem cells (ESCs) differ in their in vivo differentiation potential. While ESCs form teratomas and efficiently contribute to the development of chimeras, EpiSCs form teratomas but very rarely chimeras. In contrast to their differentiation potential, the rep...
Autores principales: | Han, Dong Wook, Tapia, Natalia, Araúzo-Bravo, Marcos J., Lim, Kyung Tae, Kim, Kee Pyo, Ko, Kinarm, Lee, Hoon Taek, Schöler, Hans R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688988/ https://www.ncbi.nlm.nih.gov/pubmed/23825671 http://dx.doi.org/10.1371/journal.pone.0067594 |
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