Cargando…

MutS homologue hMSH4: interaction with eIF3f and a role in NHEJ-mediated DSB repair

BACKGROUND: DNA mismatch repair proteins participate in diverse cellular functions including DNA damage response and repair. As a member of this protein family, the molecular mechanisms of hMSH4 in mitotic cells are poorly defined. It is known that hMSH4 is promiscuous, and among various interaction...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chu, Yen-Lin, Wu, Xiling, Xu, Yang, Her, Chengtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689047/ https://www.ncbi.nlm.nih.gov/pubmed/23725059 http://dx.doi.org/10.1186/1476-4598-12-51

Ejemplares similares

MutS Homologue hMSH5: Recombinational DSB Repair and Non-Synonymous Polymorphic Variants
por: Wu, Xiling, et al.
Publicado: (2013)

MutS Homologues hMSH4 and hMSH5: Genetic Variations, Functions, and Implications in Human Diseases
por: Clark, Nicole, et al.
Publicado: (2013)

DNA Damage Induced MutS Homologue hMSH4 Acetylation
por: Chu, Yen-Lin, et al.
Publicado: (2013)

MutS homologue hMSH5: role in cisplatin-induced DNA damage response
por: Tompkins, Joshua D, et al.
Publicado: (2012)

hMSH5 Regulates NHEJ and Averts Excessive Nucleotide Alterations at Repair Joints
por: Al-Soodani, Aneesa T., et al.
Publicado: (2022)

Loss or Somatic Mutations of hMSH2 Occur in Hereditary Nonpolyposis Colorectal Cancers with hMSH2 Germline Mutations
por: Lu, Shi‐Long, et al.
Publicado: (1996)

Population carrier frequency of hMSH2 and hMLH1 mutations
por: Dunlop, M G, et al.
Publicado: (2000)

The DNA mismatch repair gene hMSH2 is a potent coactivator of oestrogen receptor α
por: Wada-Hiraike, O, et al.
Publicado: (2005)

Expression of hMSH2 protein of the human DNA mismatch repair system in oral lichen planus
por: Pimenta, Flávio Juliano Garcia Santos, et al.
Publicado: (2004)

Expression of human DNA mismatch-repair protein, hMSH2, in patients with oral lichen planus
por: LI, HAO-BO, et al.
Publicado: (2015)

Multifaceted regulation and functions of 53BP1 in NHEJ-mediated DSB repair (Review)
por: Lei, Tiantian, et al.
Publicado: (2022)

hMSH2 and GTBP expression in advanced stage epithelial ovarian cancer
por: Ercoli, A, et al.
Publicado: (1999)

Frameshift Mutations of the hMSH6 Gene in Human Leukemia Cell Lines
por: Hosoya, Noriko, et al.
Publicado: (1998)

Somatic Hypermutation in Muts Homologue (Msh)3-, Msh6-, and Msh3/Msh6-Deficient Mice Reveals a Role for the Msh2–Msh6 Heterodimer in Modulating the Base Substitution Pattern
por: Wiesendanger, Margrit, et al.
Publicado: (2000)

hMSH2 coordinated with the expression of E2F1 promotes platinum response in epithelial ovarian cancer
por: Hu, Xiao-qian, et al.
Publicado: (2023)

Examination of Msh6- and Msh3-deficient Mice in Class Switching Reveals Overlapping and Distinct Roles of MutS Homologues in Antibody Diversification
por: Li, Ziqiang, et al.
Publicado: (2004)

Hypermethylation of mismatch repair gene hMSH2 associates with platinum-resistant disease in epithelial ovarian cancer
por: Tian, Hua, et al.
Publicado: (2019)

Expression of hMLH1 and hMSH2 proteins in ameloblastomas and tooth germs
por: Bologna-Molina, Ronell, et al.
Publicado: (2018)

Immunohistochemical analysis of expression and allelotype of mismatch repair genes (hMLH1 and hMSH2) in bladder cancer
por: Kassem, H Sh, et al.
Publicado: (2001)

Frequent loss of heterozygosity at the DNA mismatch-repair loci hMLH1 and hMSH3 in sporadic breast cancer
por: Benachenhou, N, et al.
Publicado: (1999)

Mismatch Repair Protein hMLH1, but not hMSH2, Enhances Estrogen-Induced Apoptosis of Colon Cancer Cells
por: Jin, Peng, et al.
Publicado: (2017)

Mutational Analysis of Mismatch Repair Genes, hMLH1 and hMSH2, in Sporadic Endometrial Carcinomas with Microsatellite Instability
por: Kobayashi, Kanji, et al.
Publicado: (1996)

RAG2 mutants alter DSB repair pathway choice in vivo and illuminate the nature of ‘alternative NHEJ’
por: Gigi, Vered, et al.
Publicado: (2014)

Prevalence of Pathological Germline Mutations of hMLH1 and hMSH2 Genes in Colorectal Cancer
por: Li, Dandan, et al.
Publicado: (2013)

A Mononucleotide Markers Panel to Identify hMLH1/hMSH2 Germline Mutations
por: Pedroni, M., et al.
Publicado: (2007)

Functional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposis
por: Bai, Haibo, et al.
Publicado: (2005)

Intron splice acceptor site polymorphism in the hMSH2 gene in sporadic and familial colorectal cancer
por: Palicio, M, et al.
Publicado: (2000)

hMSH2 is the most commonly mutated MMR gene in a cohort of Greek HNPCC patients
por: Apessos, A, et al.
Publicado: (2005)

Mapping of the methylation pattern of the hMSH2 promoter in colon cancer, using bisulfite genomic sequencing
por: Zhang, Hua, et al.
Publicado: (2006)

hMSH5 is a nucleocytoplasmic shuttling protein whose stability depends on its subcellular localization
por: Lahaye, François, et al.
Publicado: (2010)

Multiple Losses of MSH1, Gain of mtMutS, and Other Changes in the MutS Family of DNA Repair Proteins in Animals
por: Muthye, Viraj, et al.
Publicado: (2021)

eIF3a Regulation of NHEJ Repair Protein Synthesis and Cellular Response to Ionizing Radiation
por: Tumia, Rima, et al.
Publicado: (2020)

Link between immunoexpression of hMLH1 and hMSH2 proteins and clinical-epidemiological aspects of actinic cheilitis
por: Sarmento, Dmitry José de Santana, et al.
Publicado: (2016)

Corrigendum: eIF3a Regulation of NHEJ Repair Protein Synthesis and Cellular Response to Ionizing Radiation
por: Tumia, Rima, et al.
Publicado: (2021)

Frameshift Mutations and a Length Polymorphism in the hMSH3 Gene and the Spectrum of Microsatellite Instability in Sporadic Colon Cancer
por: Orimo, Hideo, et al.
Publicado: (1999)

The association between genetic variants in hMLH1 and hMSH2 and the development of sporadic colorectal cancer in the Danish population
por: Christensen, Lise Lotte, et al.
Publicado: (2008)

Allele loss occurs frequently at hMLH1, but rarely at hMSH2, in sporadic colorectal cancers with microsatellite instability.
por: Tomlinson, I. P., et al.
Publicado: (1996)

Deficiency of hMLH1 and hMSH2 expression is a poor prognostic factor in Early Gastric Cancer (EGC)
por: Zhu, Xueru, et al.
Publicado: (2017)

miR-1290 Is a Biomarker in DNA-Mismatch-Repair-Deficient Colon Cancer and Promotes Resistance to 5-Fluorouracil by Directly Targeting hMSH2
por: Ye, Ling, et al.
Publicado: (2017)

A missense mutation in both hMSH2 andAPC in an Ashkenazi Jewish HNPCC kindred: implications for clinical screening
por: YUAN, ZHI QIANG, et al.
Publicado: (1999)

Cannot write session to /tmp/vufind_sessions/sess_pog2ms8k5m4dfp33hhrb97rpjm