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Loss of fatty acid synthase inhibits the “HER2-PI3K/Akt axis” activity and malignant phenotype of Caco-2 cells

BACKGROUND: Fatty acid synthase (FASN) is frequently activated and overexpressed in human cancers, and plays a crucial role in the carcinogenesis of various cancers. In this study, our aims were to explore the role of FASN in regulating the “HER2-PI3K/Akt axis” activity and malignant phenotype of co...

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Detalles Bibliográficos
Autores principales:	Li, Nan, Lu, Heng, Chen, Chunyan, Bu, Xiaodong, Huang, Peilin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689055/ https://www.ncbi.nlm.nih.gov/pubmed/23725225 http://dx.doi.org/10.1186/1476-511X-12-83

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