Computational analysis of protein-protein interfaces involving an alpha helix: insights for terphenyl–like molecules binding

BACKGROUND: Protein-Protein Interactions (PPIs) are key for many cellular processes. The characterization of PPI interfaces and the prediction of putative ligand binding sites and hot spot residues are essential to design efficient small-molecule modulators of PPI. Terphenyl and its derivatives are...

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Detalles Bibliográficos
Autores principales: Isvoran, Adriana, Craciun, Dana, Martiny, Virginie, Sperandio, Olivier, Miteva, Maria A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689098/
https://www.ncbi.nlm.nih.gov/pubmed/23768251
http://dx.doi.org/10.1186/2050-6511-14-31

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