Design of Small Molecules with HIV Fusion Inhibitory Property Based on Gp41 Interaction Assay

BACKGROUND: Gp41 of HIV (Human Immunodeficiency Virus) is a protein that mediates fusion between viral and cellular membranes. The agent, T-20, which has been approved for HIV inhibition, can restrain Gp41 function in the fusion process; nevertheless, it has disadvantages like instability, high cost...

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Detalles Bibliográficos
Autores principales: Sardari, Soroush, Azadmanesh, Kayhan, Mahboudi, Fereidoun, Davood, Asghar, Vahabpour, Ruhollah, Zabihollahi, Rezvan, Gomari, Hosna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689560/
https://www.ncbi.nlm.nih.gov/pubmed/23799176

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