Compensatory Role of Inositol 5-Phosphatase INPP5B to OCRL in Primary Cilia Formation in Oculocerebrorenal Syndrome of Lowe

Inositol phosphatases are important regulators of cell signaling, polarity, and vesicular trafficking. Mutations in OCRL, an inositol polyphosphate 5-phosphatase, result in Oculocerebrorenal syndrome of Lowe, an X-linked recessive disorder that presents with congenital cataracts, glaucoma, renal dys...

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Detalles Bibliográficos
Autores principales: Luo, Na, Kumar, Akhilesh, Conwell, Michael, Weinreb, Robert N., Anderson, Ryan, Sun, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689662/
https://www.ncbi.nlm.nih.gov/pubmed/23805271
http://dx.doi.org/10.1371/journal.pone.0066727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689662/
https://www.ncbi.nlm.nih.gov/pubmed/23805271
http://dx.doi.org/10.1371/journal.pone.0066727

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