The Guinea Pig as a Model for Sporadic Alzheimer’s Disease (AD): The Impact of Cholesterol Intake on Expression of AD-Related Genes

We investigated the guinea pig, Cavia porcellus, as a model for Alzheimer’s disease (AD), both in terms of the conservation of genes involved in AD and the regulatory responses of these to a known AD risk factor - high cholesterol intake. Unlike rats and mice, guinea pigs possess an Aβ peptide seque...

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Detalles Bibliográficos
Autores principales: Sharman, Mathew J., Moussavi Nik, Seyyed H., Chen, Mengqi M., Ong, Daniel, Wijaya, Linda, Laws, Simon M., Taddei, Kevin, Newman, Morgan, Lardelli, Michael, Martins, Ralph N., Verdile, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689723/
https://www.ncbi.nlm.nih.gov/pubmed/23805206
http://dx.doi.org/10.1371/journal.pone.0066235

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