MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer

Lung cancer is the leading cause of cancer mortality in the world today. Although some advances in lung cancer therapy have been made, patient survival is still poor. MicroRNAs (miRNAs) can act as oncogenes or tumor-suppressor genes in human malignancy. The miR-34 family consists of tumor-suppressiv...

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Detalles Bibliográficos
Autores principales: Garofalo, Michela, Jeon, Young-Jun, Nuovo, Gerard J., Middleton, Justin, Secchiero, Paola, Joshi, Pooja, Alder, Hansjuerg, Nazaryan, Natalya, Di Leva, Gianpiero, Romano, Giulia, Crawford, Melissa, Nana-Sinkam, Patrick, Croce, Carlo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689725/
https://www.ncbi.nlm.nih.gov/pubmed/23805317
http://dx.doi.org/10.1371/journal.pone.0067581

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