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Identification of a Broadly Cross-Reactive Epitope in the Inner Shell of the Norovirus Capsid

Noroviruses are major pathogens associated with acute gastroenteritis. They are diverse viruses, with at least six genogroups (GI-GVI) and multiple genotypes defined by differences in the major capsid protein, VP1. This diversity has challenged the development of broadly cross-reactive vaccines as w...

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Detalles Bibliográficos
Autores principales: Parra, Gabriel I., Azure, JoLynn, Fischer, Renate, Bok, Karin, Sandoval-Jaime, Carlos, Sosnovtsev, Stanislav V., Sander, Peter, Green, Kim Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689733/
https://www.ncbi.nlm.nih.gov/pubmed/23805319
http://dx.doi.org/10.1371/journal.pone.0067592