Cargando…

A Simple and Computationally Efficient Approach to Multifactor Dimensionality Reduction Analysis of Gene-Gene Interactions for Quantitative Traits

We present an extension of the two-class multifactor dimensionality reduction (MDR) algorithm that enables detection and characterization of epistatic SNP-SNP interactions in the context of a quantitative trait. The proposed Quantitative MDR (QMDR) method handles continuous data by modifying MDR’s c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gui, Jiang, Moore, Jason H., Williams, Scott M., Andrews, Peter, Hillege, Hans L., van der Harst, Pim, Navis, Gerjan, Van Gilst, Wiek H., Asselbergs, Folkert W., Gilbert-Diamond, Diane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689797/ https://www.ncbi.nlm.nih.gov/pubmed/23805232 http://dx.doi.org/10.1371/journal.pone.0066545

Ejemplares similares

Cardiovascular Risk Associated with Interactions among Polymorphisms in Genes from the Renin-Angiotensin, Bradykinin, and Fibrinolytic Systems
por: Bentley, John P., et al.
Publicado: (2010)

The Association of the Metabolic Syndrome with PAI-1 and t-PA Levels
por: Coffey, Christopher S., et al.
Publicado: (2011)

Animal models of cardiorenal syndrome: a review
por: Szymanski, Mariusz K., et al.
Publicado: (2011)

A role for CETP TaqIB polymorphism in determining susceptibility to atrial fibrillation: a nested case control study
por: Asselbergs, Folkert W, et al.
Publicado: (2006)

Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR)
por: De, Rishika, et al.
Publicado: (2015)

Telomere biology in healthy aging and disease
por: Oeseburg, Hisko, et al.
Publicado: (2009)

Cardiac complications in patients hospitalised with COVID-19
por: Linschoten, Marijke, et al.
Publicado: (2020)

Statins in the Treatment of Chronic Heart Failure: A Systematic Review
por: van der Harst, Pim, et al.
Publicado: (2006)

Telomere Length of Circulating Leukocyte Subpopulations and Buccal Cells in Patients with Ischemic Heart Failure and Their Offspring
por: Wong, Liza S. M., et al.
Publicado: (2011)

Aging, telomeres and heart failure
por: Wong, Liza S. M., et al.
Publicado: (2010)

Renal dysfunction is associated with shorter telomere length in heart failure
por: Wong, Liza S. M., et al.
Publicado: (2009)

Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype
por: Tragante, Vinicius, et al.
Publicado: (2017)

Lower-Order Effects Adjustment in Quantitative Traits Model-Based Multifactor Dimensionality Reduction
por: Mahachie John, Jestinah M., et al.
Publicado: (2012)

Multivariate generalized multifactor dimensionality reduction to detect gene-gene interactions
por: Choi, Jiin, et al.
Publicado: (2013)

Multi-task Deep Learning of Myocardial Blood Flow and Cardiovascular Risk Traits from PET Myocardial Perfusion Imaging
por: Yeung, Ming Wai, et al.
Publicado: (2022)

An empirical fuzzy multifactor dimensionality reduction method for detecting gene-gene interactions
por: Leem, Sangseob, et al.
Publicado: (2017)

Leukocyte telomere length and left ventricular function after acute ST-elevation myocardial infarction: data from the glycometabolic intervention as adjunct to primary coronary intervention in ST elevation myocardial infarction (GIPS-III) trial
por: Haver, Vincent G., et al.
Publicado: (2015)

Hacking multifactor authentication
por: Grimes, Roger A
Publicado: (2020)

Cohort Profile Update: Lifelines, a three-generation cohort study and biobank
por: Sijtsma, Anna, et al.
Publicado: (2021)

Gene-Gene and Gene-Environmental Interactions of Childhood Asthma: A Multifactor Dimension Reduction Approach
por: Su, Ming-Wei, et al.
Publicado: (2012)

Circulating peroxiredoxin 4 and type 2 diabetes risk: the Prevention of Renal and Vascular Endstage Disease (PREVEND) study
por: Abbasi, Ali, et al.
Publicado: (2014)

The impact of coronary artery disease risk loci on ischemic heart failure severity and prognosis: association analysis in the COntrolled ROsuvastatin multiNAtional trial in heart failure (CORONA)
por: Haver, Vincent G, et al.
Publicado: (2014)

Fuzzy set-based generalized multifactor dimensionality reduction analysis of gene-gene interactions
por: Jung, Hye-Young, et al.
Publicado: (2018)

Multiobjective differential evolution-based multifactor dimensionality reduction for detecting gene–gene interactions
por: Yang, Cheng-Hong, et al.
Publicado: (2017)

Characterizing gene-gene interactions in a statistical epistasis network of twelve candidate genes for obesity
por: De, Rishika, et al.
Publicado: (2015)

Measuring leadership an assessment of the Multifactor Leadership Questionnaire
por: Batista-Foguet, Joan Manuel, et al.
Publicado: (2021)

Fibroblast Growth Factor 23 and Risk of New Onset Heart Failure With Preserved or Reduced Ejection Fraction: The PREVEND Study
por: Binnenmars, S. Heleen, et al.
Publicado: (2022)

A roadmap to multifactor dimensionality reduction methods
por: Gola, Damian, et al.
Publicado: (2016)

Risk score modeling of multiple gene to gene interactions using aggregated-multifactor dimensionality reduction
por: Dai, Hongying, et al.
Publicado: (2013)

An efficiency analysis of high-order combinations of gene–gene interactions using multifactor-dimensionality reduction
por: Yang, Cheng-Hong, et al.
Publicado: (2015)

Spatial rank-based multifactor dimensionality reduction to detect gene–gene interactions for multivariate phenotypes
por: Park, Mira, et al.
Publicado: (2021)

An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene Interactions on risk of myocardial infarction: The importance of model validation
por: Coffey, Christopher S, et al.
Publicado: (2004)

Multifactor Productivity in Health Care
por: Poisal, John A.
Publicado: (2007)

A re-appraisal of volume status and renal function impairment in chronic heart failure: combined effects of pre-renal failure and venous congestion on renal function
por: Sinkeler, Steef J., et al.
Publicado: (2011)

Discovering and Visualizing Disease-Specific Electrocardiogram Features Using Deep Learning: Proof-of-Concept in Phospholamban Gene Mutation Carriers
por: van de Leur, Rutger R., et al.
Publicado: (2021)

Emerging role of liver X receptors in cardiac pathophysiology and heart failure
por: Cannon, Megan V., et al.
Publicado: (2015)

Weighted Risk Score-Based Multifactor Dimensionality Reduction to Detect Gene-Gene Interactions in Nasopharyngeal Carcinoma
por: Li, Chao-Feng, et al.
Publicado: (2014)

A Comparative Study on Multifactor Dimensionality Reduction Methods for Detecting Gene-Gene Interactions with the Survival Phenotype
por: Lee, Seungyeoun, et al.
Publicado: (2015)

Publisher Correction: Multiobjective differential evolution-based multifactor dimensionality reduction for detecting gene–gene interactions
por: Yang, Cheng-Hong, et al.
Publicado: (2017)

Current and novel renal biomarkers in heart failure
por: Damman, Kevin, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_9c0798dl4386m4oo979ap2ooe4