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Mutant Native Outer Membrane Vesicles Combined with a Serogroup A Polysaccharide Conjugate Vaccine for Prevention of Meningococcal Epidemics in Africa

BACKGROUND: The meningococcal serogroup A (MenA) polysaccharide conjugate vaccine used in Sub-Saharan Africa does not prevent disease caused by MenW or MenX strains, which also cause epidemics in the region. We investigated the vaccine-potential of native outer membrane vesicles with over-expressed...

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Detalles Bibliográficos
Autores principales:	Pajon, Rolando, Fergus, Andrew M., Granoff, Dan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689835/ https://www.ncbi.nlm.nih.gov/pubmed/23805230 http://dx.doi.org/10.1371/journal.pone.0066536

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