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Metabolomic signatures in lipid-loaded HepaRGs reveal pathways involved in steatotic progression

OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) describes a spectrum of disorders including simple steatosis, non-alcoholic steatohepatitis, fibrosis, and cirrhosis. With the increased prevalence of obesity, and consequently NAFLD, there is a need for novel therapeutics in this area. To facili...

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Detalles Bibliográficos
Autores principales: Brown, MV, Compton, SA, Milburn, MV, Lawton, KA, Cheatham, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689848/
https://www.ncbi.nlm.nih.gov/pubmed/23512965
http://dx.doi.org/10.1002/oby.20440