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Reactivation of the inactive X chromosome in development and reprogramming
In mammals, one of the two X chromosomes of female cells is inactivated for dosage compensation between the sexes. X chromosome inactivation is initiated in early embryos by the noncoding Xist RNA. Subsequent chromatin modifications on the inactive X chromosome (Xi) lead to a remarkable stability of...
Autores principales: | Ohhata, Tatsuya, Wutz, Anton |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SP Birkhäuser Verlag Basel
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689915/ https://www.ncbi.nlm.nih.gov/pubmed/23052214 http://dx.doi.org/10.1007/s00018-012-1174-3 |
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