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Current Concepts in the Biopsy of Musculoskeletal Tumors

In the management of bone and soft tissue tumors, accurate diagnosis, using a combination of clinical, radiographic, and histological data, is critical to optimize outcome. On occasion, diagnosis can be made by careful history, physical examination, and images alone. However, the ultimate diagnosis...

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Autores principales: Errani, Costantino, Traina, Francesco, Perna, Fabrizio, Calamelli, Carlotta, Faldini, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690267/
https://www.ncbi.nlm.nih.gov/pubmed/23844403
http://dx.doi.org/10.1155/2013/538152
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author Errani, Costantino
Traina, Francesco
Perna, Fabrizio
Calamelli, Carlotta
Faldini, Cesare
author_facet Errani, Costantino
Traina, Francesco
Perna, Fabrizio
Calamelli, Carlotta
Faldini, Cesare
author_sort Errani, Costantino
collection PubMed
description In the management of bone and soft tissue tumors, accurate diagnosis, using a combination of clinical, radiographic, and histological data, is critical to optimize outcome. On occasion, diagnosis can be made by careful history, physical examination, and images alone. However, the ultimate diagnosis usually depends on histologic analysis by an experienced pathologist. Biopsy is a very important and complex surgery in the staging process. It must be done carefully, so as not to adversely affect the outcome. Technical considerations include proper location and orientation of the biopsy incision and meticulous hemostasis. It is necessary to obtain tissue for a histological diagnosis without spreading the tumor and so compromise the treatment. Furthermore, the surgeon does not open compartmental barriers, anatomic planes, joint space, and tissue area around neurovascular bundles. Nevertheless, avoid producing a hematoma. Biopsy should be carefully planned according to the site and definitive surgery and should be performed by an orthopedic surgeon with an experience in musculoskeletal oncology who will perform the definitive surgery. Improperly done, it can complicate patient care and sometimes even eliminate treatment options. Different biopsy techniques are suitable: fine-needle aspiration, core-needle biopsy, and incisional biopsy. The choice of biopsy depends on the size, the location of the lesion, and the experience of the pathologist.
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spelling pubmed-36902672013-07-09 Current Concepts in the Biopsy of Musculoskeletal Tumors Errani, Costantino Traina, Francesco Perna, Fabrizio Calamelli, Carlotta Faldini, Cesare ScientificWorldJournal Review Article In the management of bone and soft tissue tumors, accurate diagnosis, using a combination of clinical, radiographic, and histological data, is critical to optimize outcome. On occasion, diagnosis can be made by careful history, physical examination, and images alone. However, the ultimate diagnosis usually depends on histologic analysis by an experienced pathologist. Biopsy is a very important and complex surgery in the staging process. It must be done carefully, so as not to adversely affect the outcome. Technical considerations include proper location and orientation of the biopsy incision and meticulous hemostasis. It is necessary to obtain tissue for a histological diagnosis without spreading the tumor and so compromise the treatment. Furthermore, the surgeon does not open compartmental barriers, anatomic planes, joint space, and tissue area around neurovascular bundles. Nevertheless, avoid producing a hematoma. Biopsy should be carefully planned according to the site and definitive surgery and should be performed by an orthopedic surgeon with an experience in musculoskeletal oncology who will perform the definitive surgery. Improperly done, it can complicate patient care and sometimes even eliminate treatment options. Different biopsy techniques are suitable: fine-needle aspiration, core-needle biopsy, and incisional biopsy. The choice of biopsy depends on the size, the location of the lesion, and the experience of the pathologist. Hindawi Publishing Corporation 2013-06-05 /pmc/articles/PMC3690267/ /pubmed/23844403 http://dx.doi.org/10.1155/2013/538152 Text en Copyright © 2013 Costantino Errani et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Errani, Costantino
Traina, Francesco
Perna, Fabrizio
Calamelli, Carlotta
Faldini, Cesare
Current Concepts in the Biopsy of Musculoskeletal Tumors
title Current Concepts in the Biopsy of Musculoskeletal Tumors
title_full Current Concepts in the Biopsy of Musculoskeletal Tumors
title_fullStr Current Concepts in the Biopsy of Musculoskeletal Tumors
title_full_unstemmed Current Concepts in the Biopsy of Musculoskeletal Tumors
title_short Current Concepts in the Biopsy of Musculoskeletal Tumors
title_sort current concepts in the biopsy of musculoskeletal tumors
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690267/
https://www.ncbi.nlm.nih.gov/pubmed/23844403
http://dx.doi.org/10.1155/2013/538152
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