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A novel nanometric DNA thin film as a sensor for alpha radiation

The unexpected nuclear accidents have provided a challenge for scientists and engineers to develop sensitive detectors, especially for alpha radiation. Due to the high linear energy transfer value, sensors designed to detect such radiation require placement in close proximity to the radiation source...

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Detalles Bibliográficos
Autores principales: Kulkarni, Atul, Kim, Byeonghoon, Dugasani, Sreekantha Reddy, Joshirao, Pranav, Kim, Jang Ah, Vyas, Chirag, Manchanda, Vijay, Kim, Taesung, Park, Sung Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690391/
https://www.ncbi.nlm.nih.gov/pubmed/23792924
http://dx.doi.org/10.1038/srep02062
Descripción
Sumario:The unexpected nuclear accidents have provided a challenge for scientists and engineers to develop sensitive detectors, especially for alpha radiation. Due to the high linear energy transfer value, sensors designed to detect such radiation require placement in close proximity to the radiation source. Here we report the morphological changes and optical responses of artificially designed DNA thin films in response to exposure to alpha radiation as observed by an atomic force microscope, a Raman and a reflectance spectroscopes. In addition, we discuss the feasibility of a DNA thin film as a radiation sensing material. The effect of alpha radiation exposure on the DNA thin film was evaluated as a function of distance from an (241)Am source and exposure time. Significant reflected intensity changes of the exposed DNA thin film suggest that a thin film made of biomolecules can be one of promising candidates for the development of online radiation sensors.