Cell genesis and dendritic plasticity: a neuroplastic pas de deux in the onset and remission from depression

Brain neuroplasticity is increasingly considered to be an important component of both the pathology and treatment of depressive spectrum disorders. Recent studies shed light on the relevance of hippocampal cell genesis and cortico-limbic dendritic plasticity for the development and remission from de...

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Autores principales: Mateus-Pinheiro, A, Patrício, P, Bessa, J M, Sousa, N, Pinto, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690420/
https://www.ncbi.nlm.nih.gov/pubmed/23711984
http://dx.doi.org/10.1038/mp.2013.56
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author Mateus-Pinheiro, A
Patrício, P
Bessa, J M
Sousa, N
Pinto, L
author_facet Mateus-Pinheiro, A
Patrício, P
Bessa, J M
Sousa, N
Pinto, L
author_sort Mateus-Pinheiro, A
collection PubMed
description Brain neuroplasticity is increasingly considered to be an important component of both the pathology and treatment of depressive spectrum disorders. Recent studies shed light on the relevance of hippocampal cell genesis and cortico-limbic dendritic plasticity for the development and remission from depressive-like behavior. However, the neurobiological significance of neuroplastic phenomena in this context is still controversial. Here we summarize recent developments in this topic and propose an integrative interpretation of data gathered so far.
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spelling pubmed-36904202013-06-24 Cell genesis and dendritic plasticity: a neuroplastic pas de deux in the onset and remission from depression Mateus-Pinheiro, A Patrício, P Bessa, J M Sousa, N Pinto, L Mol Psychiatry Perspective Brain neuroplasticity is increasingly considered to be an important component of both the pathology and treatment of depressive spectrum disorders. Recent studies shed light on the relevance of hippocampal cell genesis and cortico-limbic dendritic plasticity for the development and remission from depressive-like behavior. However, the neurobiological significance of neuroplastic phenomena in this context is still controversial. Here we summarize recent developments in this topic and propose an integrative interpretation of data gathered so far. Nature Publishing Group 2013-07 2013-05-28 /pmc/articles/PMC3690420/ /pubmed/23711984 http://dx.doi.org/10.1038/mp.2013.56 Text en Copyright © 2013 Macmillan Publishers Limited http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Perspective
Mateus-Pinheiro, A
Patrício, P
Bessa, J M
Sousa, N
Pinto, L
Cell genesis and dendritic plasticity: a neuroplastic pas de deux in the onset and remission from depression
title Cell genesis and dendritic plasticity: a neuroplastic pas de deux in the onset and remission from depression
title_full Cell genesis and dendritic plasticity: a neuroplastic pas de deux in the onset and remission from depression
title_fullStr Cell genesis and dendritic plasticity: a neuroplastic pas de deux in the onset and remission from depression
title_full_unstemmed Cell genesis and dendritic plasticity: a neuroplastic pas de deux in the onset and remission from depression
title_short Cell genesis and dendritic plasticity: a neuroplastic pas de deux in the onset and remission from depression
title_sort cell genesis and dendritic plasticity: a neuroplastic pas de deux in the onset and remission from depression
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690420/
https://www.ncbi.nlm.nih.gov/pubmed/23711984
http://dx.doi.org/10.1038/mp.2013.56
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