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Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2
A major challenge of the post-genomics era is to define the connectivity of protein phosphorylation networks. Here, we quantitatively delineate the insulin signaling network in adipocytes by high-resolution mass spectrometry-based proteomics. These data reveal the complexity of intracellular protein...
Autores principales: | Humphrey, Sean J., Yang, Guang, Yang, Pengyi, Fazakerley, Daniel J., Stöckli, Jacqueline, Yang, Jean Y., James, David E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690479/ https://www.ncbi.nlm.nih.gov/pubmed/23684622 http://dx.doi.org/10.1016/j.cmet.2013.04.010 |
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