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Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2

A major challenge of the post-genomics era is to define the connectivity of protein phosphorylation networks. Here, we quantitatively delineate the insulin signaling network in adipocytes by high-resolution mass spectrometry-based proteomics. These data reveal the complexity of intracellular protein...

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Detalles Bibliográficos
Autores principales: Humphrey, Sean J., Yang, Guang, Yang, Pengyi, Fazakerley, Daniel J., Stöckli, Jacqueline, Yang, Jean Y., James, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690479/
https://www.ncbi.nlm.nih.gov/pubmed/23684622
http://dx.doi.org/10.1016/j.cmet.2013.04.010

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