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Biological mechanisms associated with increased perseveration and hyperactivity in a genetic mouse model of neurodevelopmental disorder

Chromosomal deletions at Xp22.3 appear to influence vulnerability to the neurodevelopmental disorders attention deficit hyperactivity disorder (ADHD) and autism. 39,X(Y*)O mice, which lack the murine orthologue of the Xp22.3 ADHD candidate gene STS (encoding steroid sulfatase), exhibit behavioural p...

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Detalles Bibliográficos
Autores principales: Trent, Simon, Dean, Rachel, Veit, Bonnie, Cassano, Tommaso, Bedse, Gaurav, Ojarikre, Obah A., Humby, Trevor, Davies, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690523/
https://www.ncbi.nlm.nih.gov/pubmed/23276394
http://dx.doi.org/10.1016/j.psyneuen.2012.12.002