Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems

There are a number of dynamic regulatory loops that maintain homeostasis of the immune and skeletal systems. In this review, we highlight a number of these regulatory interactions that contribute to maintaining homeostasis. In addition, we review data on a negative regulatory feedback loop between o...

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Detalles Bibliográficos
Autores principales: Buchwald, Zachary S., Aurora, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690642/
https://www.ncbi.nlm.nih.gov/pubmed/23840242
http://dx.doi.org/10.1155/2013/429373
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author Buchwald, Zachary S.
Aurora, Rajeev
author_facet Buchwald, Zachary S.
Aurora, Rajeev
author_sort Buchwald, Zachary S.
collection PubMed
description There are a number of dynamic regulatory loops that maintain homeostasis of the immune and skeletal systems. In this review, we highlight a number of these regulatory interactions that contribute to maintaining homeostasis. In addition, we review data on a negative regulatory feedback loop between osteoclasts and CD8 T cells that contributes to homeostasis of both the skeletal and immune systems.
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spelling pubmed-36906422013-07-09 Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems Buchwald, Zachary S. Aurora, Rajeev Clin Dev Immunol Review Article There are a number of dynamic regulatory loops that maintain homeostasis of the immune and skeletal systems. In this review, we highlight a number of these regulatory interactions that contribute to maintaining homeostasis. In addition, we review data on a negative regulatory feedback loop between osteoclasts and CD8 T cells that contributes to homeostasis of both the skeletal and immune systems. Hindawi Publishing Corporation 2013 2013-06-09 /pmc/articles/PMC3690642/ /pubmed/23840242 http://dx.doi.org/10.1155/2013/429373 Text en Copyright © 2013 Z. S. Buchwald and R. Aurora. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Buchwald, Zachary S.
Aurora, Rajeev
Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems
title Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems
title_full Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems
title_fullStr Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems
title_full_unstemmed Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems
title_short Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems
title_sort osteoclasts and cd8 t cells form a negative feedback loop that contributes to homeostasis of both the skeletal and immune systems
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690642/
https://www.ncbi.nlm.nih.gov/pubmed/23840242
http://dx.doi.org/10.1155/2013/429373
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