Long Noncoding RNAs-Related Diseases, Cancers, and Drugs

Long noncoding RNA (lncRNA) function is described in terms of related gene expressions, diseases, and cancers as well as their polymorphisms. Potential modulators of lncRNA function, including clinical drugs, natural products, and derivatives, are discussed, and bioinformatic resources are summarize...

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Detalles Bibliográficos
Autores principales: Tang, Jen-Yang, Lee, Jin-Ching, Chang, Yung-Ting, Hou, Ming-Feng, Huang, Hurng-Wern, Liaw, Chih-Chuang, Chang, Hsueh-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690748/
https://www.ncbi.nlm.nih.gov/pubmed/23843741
http://dx.doi.org/10.1155/2013/943539
Descripción
Sumario:Long noncoding RNA (lncRNA) function is described in terms of related gene expressions, diseases, and cancers as well as their polymorphisms. Potential modulators of lncRNA function, including clinical drugs, natural products, and derivatives, are discussed, and bioinformatic resources are summarized. The improving knowledge of the lncRNA regulatory network has implications not only in gene expression, diseases, and cancers, but also in the development of lncRNA-based pharmacology.

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