Cargando…

Long Noncoding RNAs-Related Diseases, Cancers, and Drugs

Long noncoding RNA (lncRNA) function is described in terms of related gene expressions, diseases, and cancers as well as their polymorphisms. Potential modulators of lncRNA function, including clinical drugs, natural products, and derivatives, are discussed, and bioinformatic resources are summarize...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Jen-Yang, Lee, Jin-Ching, Chang, Yung-Ting, Hou, Ming-Feng, Huang, Hurng-Wern, Liaw, Chih-Chuang, Chang, Hsueh-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690748/
https://www.ncbi.nlm.nih.gov/pubmed/23843741
http://dx.doi.org/10.1155/2013/943539
_version_ 1782274399143985152
author Tang, Jen-Yang
Lee, Jin-Ching
Chang, Yung-Ting
Hou, Ming-Feng
Huang, Hurng-Wern
Liaw, Chih-Chuang
Chang, Hsueh-Wei
author_facet Tang, Jen-Yang
Lee, Jin-Ching
Chang, Yung-Ting
Hou, Ming-Feng
Huang, Hurng-Wern
Liaw, Chih-Chuang
Chang, Hsueh-Wei
author_sort Tang, Jen-Yang
collection PubMed
description Long noncoding RNA (lncRNA) function is described in terms of related gene expressions, diseases, and cancers as well as their polymorphisms. Potential modulators of lncRNA function, including clinical drugs, natural products, and derivatives, are discussed, and bioinformatic resources are summarized. The improving knowledge of the lncRNA regulatory network has implications not only in gene expression, diseases, and cancers, but also in the development of lncRNA-based pharmacology.
format Online
Article
Text
id pubmed-3690748
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-36907482013-07-10 Long Noncoding RNAs-Related Diseases, Cancers, and Drugs Tang, Jen-Yang Lee, Jin-Ching Chang, Yung-Ting Hou, Ming-Feng Huang, Hurng-Wern Liaw, Chih-Chuang Chang, Hsueh-Wei ScientificWorldJournal Review Article Long noncoding RNA (lncRNA) function is described in terms of related gene expressions, diseases, and cancers as well as their polymorphisms. Potential modulators of lncRNA function, including clinical drugs, natural products, and derivatives, are discussed, and bioinformatic resources are summarized. The improving knowledge of the lncRNA regulatory network has implications not only in gene expression, diseases, and cancers, but also in the development of lncRNA-based pharmacology. Hindawi Publishing Corporation 2013-06-06 /pmc/articles/PMC3690748/ /pubmed/23843741 http://dx.doi.org/10.1155/2013/943539 Text en Copyright © 2013 Jen-Yang Tang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Tang, Jen-Yang
Lee, Jin-Ching
Chang, Yung-Ting
Hou, Ming-Feng
Huang, Hurng-Wern
Liaw, Chih-Chuang
Chang, Hsueh-Wei
Long Noncoding RNAs-Related Diseases, Cancers, and Drugs
title Long Noncoding RNAs-Related Diseases, Cancers, and Drugs
title_full Long Noncoding RNAs-Related Diseases, Cancers, and Drugs
title_fullStr Long Noncoding RNAs-Related Diseases, Cancers, and Drugs
title_full_unstemmed Long Noncoding RNAs-Related Diseases, Cancers, and Drugs
title_short Long Noncoding RNAs-Related Diseases, Cancers, and Drugs
title_sort long noncoding rnas-related diseases, cancers, and drugs
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690748/
https://www.ncbi.nlm.nih.gov/pubmed/23843741
http://dx.doi.org/10.1155/2013/943539
work_keys_str_mv AT tangjenyang longnoncodingrnasrelateddiseasescancersanddrugs
AT leejinching longnoncodingrnasrelateddiseasescancersanddrugs
AT changyungting longnoncodingrnasrelateddiseasescancersanddrugs
AT houmingfeng longnoncodingrnasrelateddiseasescancersanddrugs
AT huanghurngwern longnoncodingrnasrelateddiseasescancersanddrugs
AT liawchihchuang longnoncodingrnasrelateddiseasescancersanddrugs
AT changhsuehwei longnoncodingrnasrelateddiseasescancersanddrugs