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Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing
Among remarkable discoveries concerning propolis, such as antifungal, antiviral, and antioxidant activities, its anti-inflammatory, and mainly its antibacterial, properties deserve special attention when skin wound healing is concerned. Based on this and knowing the distinctive performance of bacter...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690832/ https://www.ncbi.nlm.nih.gov/pubmed/23840264 http://dx.doi.org/10.1155/2013/703024 |
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author | Barud, Hernane da Silva de Araújo Júnior, Adalberto Miguel Saska, Sybele Mestieri, Letícia Boldrin Campos, Juliana Alvares Duarte Bonini de Freitas, Rubens Moreno Ferreira, Nathália Ursoli Nascimento, Andresa Piacezzi Miguel, Felipe Galeti Vaz, Mirela Mara de Oliveira Lima Leite Barizon, Edna Aparecida Marquele-Oliveira, Franciane Gaspar, Ana Maria Minarelli Ribeiro, Sidney José Lima Berretta, Andresa Aparecida |
author_facet | Barud, Hernane da Silva de Araújo Júnior, Adalberto Miguel Saska, Sybele Mestieri, Letícia Boldrin Campos, Juliana Alvares Duarte Bonini de Freitas, Rubens Moreno Ferreira, Nathália Ursoli Nascimento, Andresa Piacezzi Miguel, Felipe Galeti Vaz, Mirela Mara de Oliveira Lima Leite Barizon, Edna Aparecida Marquele-Oliveira, Franciane Gaspar, Ana Maria Minarelli Ribeiro, Sidney José Lima Berretta, Andresa Aparecida |
author_sort | Barud, Hernane da Silva |
collection | PubMed |
description | Among remarkable discoveries concerning propolis, such as antifungal, antiviral, and antioxidant activities, its anti-inflammatory, and mainly its antibacterial, properties deserve special attention when skin wound healing is concerned. Based on this and knowing the distinctive performance of bacterial (BC) membranes on wound healing, in this work it is proposed to demonstrate the potent antimicrobial activity and wound healing properties of a novel propolis containing biocellulose membrane. The obtained propolis/BC membrane was able to adsorb propolis not only on the surface, but also in its interstices demonstrated by scanning electron microscopy, X-ray diffraction, Fourier transform infrared (FT-IR) spectroscopy, and thermogravidimetric assays. Additionally, the polyphenolic compounds determination and the prominent antibacterial activity in the membrane are demonstrated to be dose dependent, supporting the possibility of obtaining propolis/BC membranes at the desired concentrations, taking into consideration its application and its skin residence time. Finally, it could be suggested that propolis/BC membrane may favor tissue repair in less time and more effectively in contaminated wounds. |
format | Online Article Text |
id | pubmed-3690832 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-36908322013-07-09 Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing Barud, Hernane da Silva de Araújo Júnior, Adalberto Miguel Saska, Sybele Mestieri, Letícia Boldrin Campos, Juliana Alvares Duarte Bonini de Freitas, Rubens Moreno Ferreira, Nathália Ursoli Nascimento, Andresa Piacezzi Miguel, Felipe Galeti Vaz, Mirela Mara de Oliveira Lima Leite Barizon, Edna Aparecida Marquele-Oliveira, Franciane Gaspar, Ana Maria Minarelli Ribeiro, Sidney José Lima Berretta, Andresa Aparecida Evid Based Complement Alternat Med Research Article Among remarkable discoveries concerning propolis, such as antifungal, antiviral, and antioxidant activities, its anti-inflammatory, and mainly its antibacterial, properties deserve special attention when skin wound healing is concerned. Based on this and knowing the distinctive performance of bacterial (BC) membranes on wound healing, in this work it is proposed to demonstrate the potent antimicrobial activity and wound healing properties of a novel propolis containing biocellulose membrane. The obtained propolis/BC membrane was able to adsorb propolis not only on the surface, but also in its interstices demonstrated by scanning electron microscopy, X-ray diffraction, Fourier transform infrared (FT-IR) spectroscopy, and thermogravidimetric assays. Additionally, the polyphenolic compounds determination and the prominent antibacterial activity in the membrane are demonstrated to be dose dependent, supporting the possibility of obtaining propolis/BC membranes at the desired concentrations, taking into consideration its application and its skin residence time. Finally, it could be suggested that propolis/BC membrane may favor tissue repair in less time and more effectively in contaminated wounds. Hindawi Publishing Corporation 2013 2013-06-09 /pmc/articles/PMC3690832/ /pubmed/23840264 http://dx.doi.org/10.1155/2013/703024 Text en Copyright © 2013 Hernane da Silva Barud et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Barud, Hernane da Silva de Araújo Júnior, Adalberto Miguel Saska, Sybele Mestieri, Letícia Boldrin Campos, Juliana Alvares Duarte Bonini de Freitas, Rubens Moreno Ferreira, Nathália Ursoli Nascimento, Andresa Piacezzi Miguel, Felipe Galeti Vaz, Mirela Mara de Oliveira Lima Leite Barizon, Edna Aparecida Marquele-Oliveira, Franciane Gaspar, Ana Maria Minarelli Ribeiro, Sidney José Lima Berretta, Andresa Aparecida Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing |
title | Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing |
title_full | Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing |
title_fullStr | Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing |
title_full_unstemmed | Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing |
title_short | Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing |
title_sort | antimicrobial brazilian propolis (epp-af) containing biocellulose membranes as promising biomaterial for skin wound healing |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690832/ https://www.ncbi.nlm.nih.gov/pubmed/23840264 http://dx.doi.org/10.1155/2013/703024 |
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