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Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing

Among remarkable discoveries concerning propolis, such as antifungal, antiviral, and antioxidant activities, its anti-inflammatory, and mainly its antibacterial, properties deserve special attention when skin wound healing is concerned. Based on this and knowing the distinctive performance of bacter...

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Autores principales: Barud, Hernane da Silva, de Araújo Júnior, Adalberto Miguel, Saska, Sybele, Mestieri, Letícia Boldrin, Campos, Juliana Alvares Duarte Bonini, de Freitas, Rubens Moreno, Ferreira, Nathália Ursoli, Nascimento, Andresa Piacezzi, Miguel, Felipe Galeti, Vaz, Mirela Mara de Oliveira Lima Leite, Barizon, Edna Aparecida, Marquele-Oliveira, Franciane, Gaspar, Ana Maria Minarelli, Ribeiro, Sidney José Lima, Berretta, Andresa Aparecida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690832/
https://www.ncbi.nlm.nih.gov/pubmed/23840264
http://dx.doi.org/10.1155/2013/703024
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author Barud, Hernane da Silva
de Araújo Júnior, Adalberto Miguel
Saska, Sybele
Mestieri, Letícia Boldrin
Campos, Juliana Alvares Duarte Bonini
de Freitas, Rubens Moreno
Ferreira, Nathália Ursoli
Nascimento, Andresa Piacezzi
Miguel, Felipe Galeti
Vaz, Mirela Mara de Oliveira Lima Leite
Barizon, Edna Aparecida
Marquele-Oliveira, Franciane
Gaspar, Ana Maria Minarelli
Ribeiro, Sidney José Lima
Berretta, Andresa Aparecida
author_facet Barud, Hernane da Silva
de Araújo Júnior, Adalberto Miguel
Saska, Sybele
Mestieri, Letícia Boldrin
Campos, Juliana Alvares Duarte Bonini
de Freitas, Rubens Moreno
Ferreira, Nathália Ursoli
Nascimento, Andresa Piacezzi
Miguel, Felipe Galeti
Vaz, Mirela Mara de Oliveira Lima Leite
Barizon, Edna Aparecida
Marquele-Oliveira, Franciane
Gaspar, Ana Maria Minarelli
Ribeiro, Sidney José Lima
Berretta, Andresa Aparecida
author_sort Barud, Hernane da Silva
collection PubMed
description Among remarkable discoveries concerning propolis, such as antifungal, antiviral, and antioxidant activities, its anti-inflammatory, and mainly its antibacterial, properties deserve special attention when skin wound healing is concerned. Based on this and knowing the distinctive performance of bacterial (BC) membranes on wound healing, in this work it is proposed to demonstrate the potent antimicrobial activity and wound healing properties of a novel propolis containing biocellulose membrane. The obtained propolis/BC membrane was able to adsorb propolis not only on the surface, but also in its interstices demonstrated by scanning electron microscopy, X-ray diffraction, Fourier transform infrared (FT-IR) spectroscopy, and thermogravidimetric assays. Additionally, the polyphenolic compounds determination and the prominent antibacterial activity in the membrane are demonstrated to be dose dependent, supporting the possibility of obtaining propolis/BC membranes at the desired concentrations, taking into consideration its application and its skin residence time. Finally, it could be suggested that propolis/BC membrane may favor tissue repair in less time and more effectively in contaminated wounds.
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spelling pubmed-36908322013-07-09 Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing Barud, Hernane da Silva de Araújo Júnior, Adalberto Miguel Saska, Sybele Mestieri, Letícia Boldrin Campos, Juliana Alvares Duarte Bonini de Freitas, Rubens Moreno Ferreira, Nathália Ursoli Nascimento, Andresa Piacezzi Miguel, Felipe Galeti Vaz, Mirela Mara de Oliveira Lima Leite Barizon, Edna Aparecida Marquele-Oliveira, Franciane Gaspar, Ana Maria Minarelli Ribeiro, Sidney José Lima Berretta, Andresa Aparecida Evid Based Complement Alternat Med Research Article Among remarkable discoveries concerning propolis, such as antifungal, antiviral, and antioxidant activities, its anti-inflammatory, and mainly its antibacterial, properties deserve special attention when skin wound healing is concerned. Based on this and knowing the distinctive performance of bacterial (BC) membranes on wound healing, in this work it is proposed to demonstrate the potent antimicrobial activity and wound healing properties of a novel propolis containing biocellulose membrane. The obtained propolis/BC membrane was able to adsorb propolis not only on the surface, but also in its interstices demonstrated by scanning electron microscopy, X-ray diffraction, Fourier transform infrared (FT-IR) spectroscopy, and thermogravidimetric assays. Additionally, the polyphenolic compounds determination and the prominent antibacterial activity in the membrane are demonstrated to be dose dependent, supporting the possibility of obtaining propolis/BC membranes at the desired concentrations, taking into consideration its application and its skin residence time. Finally, it could be suggested that propolis/BC membrane may favor tissue repair in less time and more effectively in contaminated wounds. Hindawi Publishing Corporation 2013 2013-06-09 /pmc/articles/PMC3690832/ /pubmed/23840264 http://dx.doi.org/10.1155/2013/703024 Text en Copyright © 2013 Hernane da Silva Barud et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Barud, Hernane da Silva
de Araújo Júnior, Adalberto Miguel
Saska, Sybele
Mestieri, Letícia Boldrin
Campos, Juliana Alvares Duarte Bonini
de Freitas, Rubens Moreno
Ferreira, Nathália Ursoli
Nascimento, Andresa Piacezzi
Miguel, Felipe Galeti
Vaz, Mirela Mara de Oliveira Lima Leite
Barizon, Edna Aparecida
Marquele-Oliveira, Franciane
Gaspar, Ana Maria Minarelli
Ribeiro, Sidney José Lima
Berretta, Andresa Aparecida
Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing
title Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing
title_full Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing
title_fullStr Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing
title_full_unstemmed Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing
title_short Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing
title_sort antimicrobial brazilian propolis (epp-af) containing biocellulose membranes as promising biomaterial for skin wound healing
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690832/
https://www.ncbi.nlm.nih.gov/pubmed/23840264
http://dx.doi.org/10.1155/2013/703024
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