ATP Antagonizes Thrombin-Induced Signal Transduction through 12(S)-HETE and cAMP

In this study we have investigated the role of extracellular ATP on thrombin induced-platelet aggregation (TIPA) in washed human platelets. ATP inhibited TIPA in a dose-dependent manner and this inhibition was abolished by apyrase but not by adenosine deaminase (ADA) and it was reversed by extracell...

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Detalles Bibliográficos
Autores principales: Burzaco, Jaione, Conde, Manuel, Parada, Luis A., Zugaza, José L., Dehaye, Jean-Paul, Marino, Aida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691129/
https://www.ncbi.nlm.nih.gov/pubmed/23826207
http://dx.doi.org/10.1371/journal.pone.0067117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691129/
https://www.ncbi.nlm.nih.gov/pubmed/23826207
http://dx.doi.org/10.1371/journal.pone.0067117

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