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ATP Antagonizes Thrombin-Induced Signal Transduction through 12(S)-HETE and cAMP

In this study we have investigated the role of extracellular ATP on thrombin induced-platelet aggregation (TIPA) in washed human platelets. ATP inhibited TIPA in a dose-dependent manner and this inhibition was abolished by apyrase but not by adenosine deaminase (ADA) and it was reversed by extracell...

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Detalles Bibliográficos
Autores principales:	Burzaco, Jaione, Conde, Manuel, Parada, Luis A., Zugaza, José L., Dehaye, Jean-Paul, Marino, Aida
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691129/ https://www.ncbi.nlm.nih.gov/pubmed/23826207 http://dx.doi.org/10.1371/journal.pone.0067117

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