SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is characterized by defective immune tolerance combined with immune cell hyperactivity resulting in the production of pathogenic autoantibodies. Previous gene expression studies employing whole blood or peripheral blood mononucl...

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Detalles Bibliográficos
Autores principales: Becker, Amy M., Dao, Kathryn H., Han, Bobby Kwanghoon, Kornu, Roger, Lakhanpal, Shuchi, Mobley, Angela B., Li, Quan-Zhen, Lian, Yun, Wu, Tianfu, Reimold, Andreas M., Olsen, Nancy J., Karp, David R., Chowdhury, Fatema Z., Farrar, J. David, Satterthwaite, Anne B., Mohan, Chandra, Lipsky, Peter E., Wakeland, Edward K., Davis, Laurie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691135/
https://www.ncbi.nlm.nih.gov/pubmed/23826184
http://dx.doi.org/10.1371/journal.pone.0067003

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