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Regional Differences in Islet Distribution in the Human Pancreas - Preferential Beta-Cell Loss in the Head Region in Patients with Type 2 Diabetes

While regional heterogeneity in islet distribution has been well studied in rodents, less is known about human pancreatic histology. To fill gaps in our understanding, regional differences in the adult human pancreas were quantitatively analyzed including the pathogenesis of type 2 diabetes (T2D). C...

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Detalles Bibliográficos
Autores principales: Wang, Xiaojun, Misawa, Ryosuke, Zielinski, Mark C., Cowen, Peter, Jo, Junghyo, Periwal, Vipul, Ricordi, Camillo, Khan, Aisha, Szust, Joel, Shen, Junhui, Millis, J. Michael, Witkowski, Piotr, Hara, Manami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691162/
https://www.ncbi.nlm.nih.gov/pubmed/23826303
http://dx.doi.org/10.1371/journal.pone.0067454