Cargando…

Sulforaphane Restores Cellular Glutathione Levels and Reduces Chronic Periodontitis Neutrophil Hyperactivity In Vitro

The production of high levels of reactive oxygen species by neutrophils is associated with the local and systemic destructive phenotype found in the chronic inflammatory disease periodontitis. In the present study, we investigated the ability of sulforaphane (SFN) to restore cellular glutathione lev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dias, Irundika H. K., Chapple, Ian L. C., Milward, Mike, Grant, Melissa M., Hill, Eric, Brown, James, Griffiths, Helen R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691189/ https://www.ncbi.nlm.nih.gov/pubmed/23826097 http://dx.doi.org/10.1371/journal.pone.0066407

Ejemplares similares

Impaired neutrophil directional chemotactic accuracy in chronic periodontitis patients
por: Roberts, Helen M, et al.
Publicado: (2015)

Oxidative stress links periodontal inflammation and renal function
por: Sharma, Praveen, et al.
Publicado: (2021)

Healthy ageing and depletion of intracellular glutathione influences T cell membrane thioredoxin-1 levels and cytokine secretion
por: Carilho Torrao, Rita Barreto Duarte, et al.
Publicado: (2013)

Nrf2 activation supports cell survival during hypoxia and hypoxia/reoxygenation in cardiomyoblasts; the roles of reactive oxygen and nitrogen species()
por: Kolamunne, Rajitha T, et al.
Publicado: (2013)

Oxidized LDL lipids increase β-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation
por: Dias, Irundika H.K., et al.
Publicado: (2014)

Sulforaphane Inhibits Inflammatory Responses of Primary Human T-Cells by Increasing ROS and Depleting Glutathione
por: Liang, Jie, et al.
Publicado: (2018)

Porphyromonas gingivalis gingipains cause defective macrophage migration towards apoptotic cells and inhibit phagocytosis of primary apoptotic neutrophils
por: Castro, Sowmya A, et al.
Publicado: (2017)

Sulforaphane Induces Oxidative Stress and Death by p53-Independent Mechanism: Implication of Impaired Glutathione Recycling
por: Ferreira de Oliveira, José Miguel P., et al.
Publicado: (2014)

Redox regulation of protein damage in plasma
por: Griffiths, Helen R., et al.
Publicado: (2014)

miRNA 933 Expression by Endothelial Cells is Increased by 27-Hydroxycholesterol and is More Prevalent in Plasma from Dementia Patients
por: Dias, Irundika H.K., et al.
Publicado: (2018)

Impact of Gingivitis on Circulating Neutrophil Reactivity and Gingival Crevicular Fluid Inflammatory Proteins
por: Roberts, Helen M., et al.
Publicado: (2022)

The antioxidant master glutathione and periodontal health
por: Bains, Vivek Kumar, et al.
Publicado: (2015)

Glutathione Restores the Mechanism of Synaptic Plasticity in Aged Mice to That of the Adult
por: Robillard, Julie M., et al.
Publicado: (2011)

Sulforaphane salads
por: Tiwari, Ashok Kumar
Publicado: (2018)

Impact of Bariatric Surgical Intervention on Peripheral Blood Neutrophil (PBN) Function in Obesity
por: Roberts, Helen M., et al.
Publicado: (2017)

Factors Influencing Sulforaphane Content in Broccoli Sprouts and Subsequent Sulforaphane Extraction
por: Tříska, Jan, et al.
Publicado: (2021)

How to Increase Cellular Glutathione
por: Giustarini, Daniela, et al.
Publicado: (2023)

Chemopreventive activity of sulforaphane
por: Jiang, Xin, et al.
Publicado: (2018)

The oral health and periodontal diseases awareness and knowledge in the Iraqi population: Online‐based survey
por: Abdulbaqi, Hayder R., et al.
Publicado: (2020)

Eradication of Helicobacter pylori Restores Glutathione S‐Transferase Activity and Glutathione Levels in Antral Mucosa
por: van Oijen, Arnoud H. A. M., et al.
Publicado: (2001)

Discovery, validation, and diagnostic ability of multiple protein‐based biomarkers in saliva and gingival crevicular fluid to distinguish between health and periodontal diseases
por: Grant, Melissa M., et al.
Publicado: (2022)

CD18 Mediates Neutrophil Imperviousness to the Aggregatibacter actinomycetemcomitans JP2 Clone in Molar-Incisor Pattern Periodontitis
por: Hashai, Koren, et al.
Publicado: (2022)

Comparison of Pharmacokinetics and Anti-Pulmonary Fibrosis-Related Effects of Sulforaphane and Sulforaphane N-acetylcysteine
por: Son, Eun Suk, et al.
Publicado: (2021)

Classic vs. Novel Antibacterial Approaches for Eradicating Dental Biofilm as Adjunct to Periodontal Debridement: An Evidence-Based Overview
por: Abdulkareem, Ali, et al.
Publicado: (2021)

Cellular Compartmentalization, Glutathione Transport and Its Relevance in Some Pathologies
por: Vázquez-Meza, Héctor, et al.
Publicado: (2023)

Interaction of Sulforaphane with DNA and RNA
por: Abassi Joozdani, Farzaneh, et al.
Publicado: (2015)

The neuroprotective mechanisms and effects of sulforaphane
por: Klomparens, Eric A, et al.
Publicado: (2019)

Efficacy of Sulforaphane in Neurodegenerative Diseases
por: Schepici, Giovanni, et al.
Publicado: (2020)

Intermittent treatment with farnesyltransferase inhibitor and sulforaphane improves cellular homeostasis in Hutchinson-Gilford progeria fibroblasts
por: Gabriel, Diana, et al.
Publicado: (2017)

Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage
por: Hariton, Florence, et al.
Publicado: (2018)

Neutrophils’ Contribution to Periodontitis and Periodontitis-Associated Cardiovascular Diseases
por: Bassani, Barbara, et al.
Publicado: (2023)

A proof-of-concept clinical study examining the NRF2 activator sulforaphane against neutrophilic airway inflammation
por: Duran, Charity G., et al.
Publicado: (2016)

Neutrophil Functions in Periodontal Homeostasis
por: Cortés-Vieyra, Ricarda, et al.
Publicado: (2016)

Neutrophil Extracellular Traps in Periodontitis
por: Magán-Fernández, Antonio, et al.
Publicado: (2020)

Neutrophils Orchestrate the Periodontal Pocket
por: Vitkov, Ljubomir, et al.
Publicado: (2021)

Evaluation of non-surgical therapy on glutathione levels in chronic periodontitis
por: Palwankar, Pooja, et al.
Publicado: (2015)

Release of Active Peptidyl Arginine Deiminases by Neutrophils Can Explain Production of Extracellular Citrullinated Autoantigens in Rheumatoid Arthritis Synovial Fluid
por: Spengler, Julia, et al.
Publicado: (2015)

Prodrug Approach for Increasing Cellular Glutathione Levels
por: Cacciatore, Ivana, et al.
Publicado: (2010)

Mechanism for the attenuation of neutrophil and complement hyperactivity by MSC exosomes
por: Loh, Jia Tong, et al.
Publicado: (2022)

Interactions Between Neutrophils and Periodontal Pathogens in Late-Onset Periodontitis
por: Jiang, Qingsong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ru5arjhplob21vd4179hb8ap0b