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Postpartum Haemorrhage in Canada and France: A Population-Based Comparison

OBJECTIVE: Maternal mortality ratio due to postpartum haemorrhage (PPH) is higher in France than in Canada. We explored this difference by comparing PPH features between these two countries. METHODS: Using data between 2004 and 2006, we compared the incidence, risk factors, causes and use of second-...

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Autores principales: Bonnet, Marie-Pierre, Basso, Olga, Bouvier-Colle, Marie-Hélène, Dupont, Corinne, Rudigoz, René-Charles, Fuhrer, Rebecca, Deneux-Tharaux, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691240/
https://www.ncbi.nlm.nih.gov/pubmed/23826165
http://dx.doi.org/10.1371/journal.pone.0066882
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author Bonnet, Marie-Pierre
Basso, Olga
Bouvier-Colle, Marie-Hélène
Dupont, Corinne
Rudigoz, René-Charles
Fuhrer, Rebecca
Deneux-Tharaux, Catherine
author_facet Bonnet, Marie-Pierre
Basso, Olga
Bouvier-Colle, Marie-Hélène
Dupont, Corinne
Rudigoz, René-Charles
Fuhrer, Rebecca
Deneux-Tharaux, Catherine
author_sort Bonnet, Marie-Pierre
collection PubMed
description OBJECTIVE: Maternal mortality ratio due to postpartum haemorrhage (PPH) is higher in France than in Canada. We explored this difference by comparing PPH features between these two countries. METHODS: Using data between 2004 and 2006, we compared the incidence, risk factors, causes and use of second-line treatments, of PPH between France (N = 6,660 PPH) and Canada (N = 9,838 PPH). We assessed factors associated with PPH through multivariate logistic models. RESULTS: PPH incidence, overall (4.8% (95% CI 4.7–4.9) in Canada and 4.5% (95% CI 4.4–4.7) in France), and after vaginal delivery (5.3% (95%CI 5.2–5.4) in Canada and 4.8 (95%CI 4.7–4.9) in France), were significantly higher in Canada than in France, but not after caesarean delivery. Women delivering without PPH were similar between the two populations, except for macrosomia (11% in Canada, 7% in France, p<0.001), caesarean delivery (27% in Canada, 18% in France, p<0.001), and episiotomy (17% in Canada, 34% in France, p<0.001). After vaginal delivery, factors strongly associated with PPH were multiple pregnancy, operative delivery and macrosomia in both populations, and episiotomy only in France (Odds Ratio 1.39 (95% CI 1.23–1.57)). The use of second-line treatments for PPH management was significantly more frequent in France than in Canada after both vaginal and caesarean delivery. CONCLUSION: PPH incidence was not higher in France than in Canada and there was no substantial difference in PPH risk factors between the 2 countries. Greater use of second-line treatments in PPH management in France suggests a more frequent failure of first-line treatments and a higher rate of severe PPH, which may be involved in the higher maternal mortality ratio due to PPH.
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spelling pubmed-36912402013-07-03 Postpartum Haemorrhage in Canada and France: A Population-Based Comparison Bonnet, Marie-Pierre Basso, Olga Bouvier-Colle, Marie-Hélène Dupont, Corinne Rudigoz, René-Charles Fuhrer, Rebecca Deneux-Tharaux, Catherine PLoS One Research Article OBJECTIVE: Maternal mortality ratio due to postpartum haemorrhage (PPH) is higher in France than in Canada. We explored this difference by comparing PPH features between these two countries. METHODS: Using data between 2004 and 2006, we compared the incidence, risk factors, causes and use of second-line treatments, of PPH between France (N = 6,660 PPH) and Canada (N = 9,838 PPH). We assessed factors associated with PPH through multivariate logistic models. RESULTS: PPH incidence, overall (4.8% (95% CI 4.7–4.9) in Canada and 4.5% (95% CI 4.4–4.7) in France), and after vaginal delivery (5.3% (95%CI 5.2–5.4) in Canada and 4.8 (95%CI 4.7–4.9) in France), were significantly higher in Canada than in France, but not after caesarean delivery. Women delivering without PPH were similar between the two populations, except for macrosomia (11% in Canada, 7% in France, p<0.001), caesarean delivery (27% in Canada, 18% in France, p<0.001), and episiotomy (17% in Canada, 34% in France, p<0.001). After vaginal delivery, factors strongly associated with PPH were multiple pregnancy, operative delivery and macrosomia in both populations, and episiotomy only in France (Odds Ratio 1.39 (95% CI 1.23–1.57)). The use of second-line treatments for PPH management was significantly more frequent in France than in Canada after both vaginal and caesarean delivery. CONCLUSION: PPH incidence was not higher in France than in Canada and there was no substantial difference in PPH risk factors between the 2 countries. Greater use of second-line treatments in PPH management in France suggests a more frequent failure of first-line treatments and a higher rate of severe PPH, which may be involved in the higher maternal mortality ratio due to PPH. Public Library of Science 2013-06-24 /pmc/articles/PMC3691240/ /pubmed/23826165 http://dx.doi.org/10.1371/journal.pone.0066882 Text en © 2013 Bonnet et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Bonnet, Marie-Pierre
Basso, Olga
Bouvier-Colle, Marie-Hélène
Dupont, Corinne
Rudigoz, René-Charles
Fuhrer, Rebecca
Deneux-Tharaux, Catherine
Postpartum Haemorrhage in Canada and France: A Population-Based Comparison
title Postpartum Haemorrhage in Canada and France: A Population-Based Comparison
title_full Postpartum Haemorrhage in Canada and France: A Population-Based Comparison
title_fullStr Postpartum Haemorrhage in Canada and France: A Population-Based Comparison
title_full_unstemmed Postpartum Haemorrhage in Canada and France: A Population-Based Comparison
title_short Postpartum Haemorrhage in Canada and France: A Population-Based Comparison
title_sort postpartum haemorrhage in canada and france: a population-based comparison
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691240/
https://www.ncbi.nlm.nih.gov/pubmed/23826165
http://dx.doi.org/10.1371/journal.pone.0066882
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