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Postpartum Haemorrhage in Canada and France: A Population-Based Comparison
OBJECTIVE: Maternal mortality ratio due to postpartum haemorrhage (PPH) is higher in France than in Canada. We explored this difference by comparing PPH features between these two countries. METHODS: Using data between 2004 and 2006, we compared the incidence, risk factors, causes and use of second-...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691240/ https://www.ncbi.nlm.nih.gov/pubmed/23826165 http://dx.doi.org/10.1371/journal.pone.0066882 |
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author | Bonnet, Marie-Pierre Basso, Olga Bouvier-Colle, Marie-Hélène Dupont, Corinne Rudigoz, René-Charles Fuhrer, Rebecca Deneux-Tharaux, Catherine |
author_facet | Bonnet, Marie-Pierre Basso, Olga Bouvier-Colle, Marie-Hélène Dupont, Corinne Rudigoz, René-Charles Fuhrer, Rebecca Deneux-Tharaux, Catherine |
author_sort | Bonnet, Marie-Pierre |
collection | PubMed |
description | OBJECTIVE: Maternal mortality ratio due to postpartum haemorrhage (PPH) is higher in France than in Canada. We explored this difference by comparing PPH features between these two countries. METHODS: Using data between 2004 and 2006, we compared the incidence, risk factors, causes and use of second-line treatments, of PPH between France (N = 6,660 PPH) and Canada (N = 9,838 PPH). We assessed factors associated with PPH through multivariate logistic models. RESULTS: PPH incidence, overall (4.8% (95% CI 4.7–4.9) in Canada and 4.5% (95% CI 4.4–4.7) in France), and after vaginal delivery (5.3% (95%CI 5.2–5.4) in Canada and 4.8 (95%CI 4.7–4.9) in France), were significantly higher in Canada than in France, but not after caesarean delivery. Women delivering without PPH were similar between the two populations, except for macrosomia (11% in Canada, 7% in France, p<0.001), caesarean delivery (27% in Canada, 18% in France, p<0.001), and episiotomy (17% in Canada, 34% in France, p<0.001). After vaginal delivery, factors strongly associated with PPH were multiple pregnancy, operative delivery and macrosomia in both populations, and episiotomy only in France (Odds Ratio 1.39 (95% CI 1.23–1.57)). The use of second-line treatments for PPH management was significantly more frequent in France than in Canada after both vaginal and caesarean delivery. CONCLUSION: PPH incidence was not higher in France than in Canada and there was no substantial difference in PPH risk factors between the 2 countries. Greater use of second-line treatments in PPH management in France suggests a more frequent failure of first-line treatments and a higher rate of severe PPH, which may be involved in the higher maternal mortality ratio due to PPH. |
format | Online Article Text |
id | pubmed-3691240 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-36912402013-07-03 Postpartum Haemorrhage in Canada and France: A Population-Based Comparison Bonnet, Marie-Pierre Basso, Olga Bouvier-Colle, Marie-Hélène Dupont, Corinne Rudigoz, René-Charles Fuhrer, Rebecca Deneux-Tharaux, Catherine PLoS One Research Article OBJECTIVE: Maternal mortality ratio due to postpartum haemorrhage (PPH) is higher in France than in Canada. We explored this difference by comparing PPH features between these two countries. METHODS: Using data between 2004 and 2006, we compared the incidence, risk factors, causes and use of second-line treatments, of PPH between France (N = 6,660 PPH) and Canada (N = 9,838 PPH). We assessed factors associated with PPH through multivariate logistic models. RESULTS: PPH incidence, overall (4.8% (95% CI 4.7–4.9) in Canada and 4.5% (95% CI 4.4–4.7) in France), and after vaginal delivery (5.3% (95%CI 5.2–5.4) in Canada and 4.8 (95%CI 4.7–4.9) in France), were significantly higher in Canada than in France, but not after caesarean delivery. Women delivering without PPH were similar between the two populations, except for macrosomia (11% in Canada, 7% in France, p<0.001), caesarean delivery (27% in Canada, 18% in France, p<0.001), and episiotomy (17% in Canada, 34% in France, p<0.001). After vaginal delivery, factors strongly associated with PPH were multiple pregnancy, operative delivery and macrosomia in both populations, and episiotomy only in France (Odds Ratio 1.39 (95% CI 1.23–1.57)). The use of second-line treatments for PPH management was significantly more frequent in France than in Canada after both vaginal and caesarean delivery. CONCLUSION: PPH incidence was not higher in France than in Canada and there was no substantial difference in PPH risk factors between the 2 countries. Greater use of second-line treatments in PPH management in France suggests a more frequent failure of first-line treatments and a higher rate of severe PPH, which may be involved in the higher maternal mortality ratio due to PPH. Public Library of Science 2013-06-24 /pmc/articles/PMC3691240/ /pubmed/23826165 http://dx.doi.org/10.1371/journal.pone.0066882 Text en © 2013 Bonnet et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Bonnet, Marie-Pierre Basso, Olga Bouvier-Colle, Marie-Hélène Dupont, Corinne Rudigoz, René-Charles Fuhrer, Rebecca Deneux-Tharaux, Catherine Postpartum Haemorrhage in Canada and France: A Population-Based Comparison |
title | Postpartum Haemorrhage in Canada and France: A Population-Based Comparison |
title_full | Postpartum Haemorrhage in Canada and France: A Population-Based Comparison |
title_fullStr | Postpartum Haemorrhage in Canada and France: A Population-Based Comparison |
title_full_unstemmed | Postpartum Haemorrhage in Canada and France: A Population-Based Comparison |
title_short | Postpartum Haemorrhage in Canada and France: A Population-Based Comparison |
title_sort | postpartum haemorrhage in canada and france: a population-based comparison |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691240/ https://www.ncbi.nlm.nih.gov/pubmed/23826165 http://dx.doi.org/10.1371/journal.pone.0066882 |
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