Small Ruminant Nor98 Prions Share Biochemical Features with Human Gerstmann-Sträussler-Scheinker Disease and Variably Protease-Sensitive Prionopathy

Prion diseases are classically characterized by the accumulation of pathological prion protein (PrP(Sc)) with the protease resistant C-terminal fragment (PrP(res)) of 27–30 kDa. However, in both humans and animals, prion diseases with atypical biochemical features, characterized by PK-resistant PrP...

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Detalles Bibliográficos
Autores principales: Pirisinu, Laura, Nonno, Romolo, Esposito, Elena, Benestad, Sylvie L., Gambetti, Pierluigi, Agrimi, Umberto, Zou, Wen-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691246/
https://www.ncbi.nlm.nih.gov/pubmed/23826096
http://dx.doi.org/10.1371/journal.pone.0066405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691246/
https://www.ncbi.nlm.nih.gov/pubmed/23826096
http://dx.doi.org/10.1371/journal.pone.0066405

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