Variation in Both IL28B and KIR2DS3 Genes Influence Pegylated Interferon and Ribavirin Hepatitis C Treatment Outcome in HIV-1 Co-Infection

Pegylated-IFN and ribavirin remains the current treatment for chronic HCV infection in patients co-infected with HIV-1, but this regimen has low efficacy rates, particularly for HCV genotype 1/4 infection, has severe side effects and is extremely costly. Therefore, accurate prediction of treatment r...

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Detalles Bibliográficos
Autores principales: Keane, Ciara, O’Shea, Daire, Reiberger, Thomas, Peck-Radosavljevic, Markus, Farrell, Gillian, Bergin, Colm, Gardiner, Clair M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691248/
https://www.ncbi.nlm.nih.gov/pubmed/23826153
http://dx.doi.org/10.1371/journal.pone.0066831

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