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Structure of the Human Telomeric Stn1-Ten1 Capping Complex

The identification of the human homologue of the yeast CST in 2009 posed a new challenge in our understanding of the mechanism of telomere capping in higher eukaryotes. The high-resolution structure of the human Stn1-Ten1 (hStn1-Ten1) complex presented here reveals that hStn1 consists of an OB domai...

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Detalles Bibliográficos
Autores principales: Bryan, Christopher, Rice, Cory, Harkisheimer, Michael, Schultz, David C., Skordalakes, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691326/
https://www.ncbi.nlm.nih.gov/pubmed/23826127
http://dx.doi.org/10.1371/journal.pone.0066756