Contribution of the KCa3.1 channel–calmodulin interactions to the regulation of the KCa3.1 gating process

The Ca(2+)-activated potassium channel of intermediate conductance, KCa3.1, is now emerging as a therapeutic target for a large variety of health disorders. The Ca(2+) sensitivity of KCa3.1 is conferred by the Ca(2+)-binding protein calmodulin (CaM), with the CaM C-lobe constitutively bound to an in...

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Detalles Bibliográficos
Autores principales: Morales, Patricia, Garneau, Line, Klein, Hélène, Lavoie, Marie-France, Parent, Lucie, Sauvé, Rémy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691446/
https://www.ncbi.nlm.nih.gov/pubmed/23797421
http://dx.doi.org/10.1085/jgp.201210933

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