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Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules

Fission and fusion reactions determine mitochondrial morphology and function. Dynamin-related protein 1 (Drp1) is a guanosine triphosphate–hydrolyzing mechanoenzyme important for mitochondrial fission and programmed cell death. Drp1 is subject to alternative splicing of three exons with previously u...

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Detalles Bibliográficos
Autores principales: Strack, Stefan, Wilson, Theodore J., Cribbs, J. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691453/
https://www.ncbi.nlm.nih.gov/pubmed/23798729
http://dx.doi.org/10.1083/jcb.201210045