Imaging cell biology in live animals: Ready for prime time

Time-lapse fluorescence microscopy is one of the main tools used to image subcellular structures in living cells. Yet for decades it has been applied primarily to in vitro model systems. Thanks to the most recent advancements in intravital microscopy, this approach has finally been extended to live...

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Detalles Bibliográficos
Autores principales: Weigert, Roberto, Porat-Shliom, Natalie, Amornphimoltham, Panomwat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691462/
https://www.ncbi.nlm.nih.gov/pubmed/23798727
http://dx.doi.org/10.1083/jcb.201212130
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author Weigert, Roberto
Porat-Shliom, Natalie
Amornphimoltham, Panomwat
author_facet Weigert, Roberto
Porat-Shliom, Natalie
Amornphimoltham, Panomwat
author_sort Weigert, Roberto
collection PubMed
description Time-lapse fluorescence microscopy is one of the main tools used to image subcellular structures in living cells. Yet for decades it has been applied primarily to in vitro model systems. Thanks to the most recent advancements in intravital microscopy, this approach has finally been extended to live rodents. This represents a major breakthrough that will provide unprecedented new opportunities to study mammalian cell biology in vivo and has already provided new insight in the fields of neurobiology, immunology, and cancer biology.
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spelling pubmed-36914622013-12-24 Imaging cell biology in live animals: Ready for prime time Weigert, Roberto Porat-Shliom, Natalie Amornphimoltham, Panomwat J Cell Biol Reviews Time-lapse fluorescence microscopy is one of the main tools used to image subcellular structures in living cells. Yet for decades it has been applied primarily to in vitro model systems. Thanks to the most recent advancements in intravital microscopy, this approach has finally been extended to live rodents. This represents a major breakthrough that will provide unprecedented new opportunities to study mammalian cell biology in vivo and has already provided new insight in the fields of neurobiology, immunology, and cancer biology. The Rockefeller University Press 2013-06-24 /pmc/articles/PMC3691462/ /pubmed/23798727 http://dx.doi.org/10.1083/jcb.201212130 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Weigert, Roberto
Porat-Shliom, Natalie
Amornphimoltham, Panomwat
Imaging cell biology in live animals: Ready for prime time
title Imaging cell biology in live animals: Ready for prime time
title_full Imaging cell biology in live animals: Ready for prime time
title_fullStr Imaging cell biology in live animals: Ready for prime time
title_full_unstemmed Imaging cell biology in live animals: Ready for prime time
title_short Imaging cell biology in live animals: Ready for prime time
title_sort imaging cell biology in live animals: ready for prime time
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691462/
https://www.ncbi.nlm.nih.gov/pubmed/23798727
http://dx.doi.org/10.1083/jcb.201212130
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