Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of high-dose intravenous ascorbic acid in patients with advanced cancer

PURPOSE: This phase I clinical trial evaluated the safety, tolerability, and pharmacokinetics of high-dose intravenous (i.v.) ascorbic acid as a monotherapy in patients with advanced solid tumors refractory to standard therapy. METHODS: Five cohorts of three patients received i.v. ascorbic acid admi...

Descripción completa

Detalles Bibliográficos
Autores principales: Stephenson, Christopher M., Levin, Robert D., Spector, Thomas, Lis, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691494/
https://www.ncbi.nlm.nih.gov/pubmed/23670640
http://dx.doi.org/10.1007/s00280-013-2179-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691494/
https://www.ncbi.nlm.nih.gov/pubmed/23670640
http://dx.doi.org/10.1007/s00280-013-2179-9

Ejemplares similares