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Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of high-dose intravenous ascorbic acid in patients with advanced cancer

PURPOSE: This phase I clinical trial evaluated the safety, tolerability, and pharmacokinetics of high-dose intravenous (i.v.) ascorbic acid as a monotherapy in patients with advanced solid tumors refractory to standard therapy. METHODS: Five cohorts of three patients received i.v. ascorbic acid admi...

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Detalles Bibliográficos
Autores principales:	Stephenson, Christopher M., Levin, Robert D., Spector, Thomas, Lis, Christopher G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691494/ https://www.ncbi.nlm.nih.gov/pubmed/23670640 http://dx.doi.org/10.1007/s00280-013-2179-9

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