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Prospects for circumventing aminoglycoside kinase mediated antibiotic resistance

Aminoglycosides are a class of antibiotics with a broad spectrum of antimicrobial activity. Unfortunately, resistance in clinical isolates is pervasive, rendering many aminoglycosides ineffective. The most widely disseminated means of resistance to this class of antibiotics is inactivation of the dr...

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Detalles Bibliográficos
Autores principales:	Shi, Kun, Caldwell, Shane J., Fong, Desiree H., Berghuis, Albert M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691515/ https://www.ncbi.nlm.nih.gov/pubmed/23805415 http://dx.doi.org/10.3389/fcimb.2013.00022

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