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Incorporating phylogenetic-based covarying mutations into RNAalifold for RNA consensus structure prediction
BACKGROUND: RNAalifold, a popular computational method for RNA consensus structure prediction, incorporates covarying mutations into a thermodynamic model to fold the aligned RNA sequences. When quantifying covariance, it evaluates conserved signals of two aligned columns with base-pairing rules. Th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691524/ https://www.ncbi.nlm.nih.gov/pubmed/23621982 http://dx.doi.org/10.1186/1471-2105-14-142 |