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Incorporating phylogenetic-based covarying mutations into RNAalifold for RNA consensus structure prediction

BACKGROUND: RNAalifold, a popular computational method for RNA consensus structure prediction, incorporates covarying mutations into a thermodynamic model to fold the aligned RNA sequences. When quantifying covariance, it evaluates conserved signals of two aligned columns with base-pairing rules. Th...

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Detalles Bibliográficos
Autores principales:	Ge, Ping, Zhang, Shaojie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691524/ https://www.ncbi.nlm.nih.gov/pubmed/23621982 http://dx.doi.org/10.1186/1471-2105-14-142

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