Cargando…
Canonical Wnt signaling protects hippocampal neurons from Aβ oligomers: role of non-canonical Wnt-5a/Ca(2+) in mitochondrial dynamics
Alzheimer's disease (AD) is the most common type of age-related dementia. The disease is characterized by a progressive loss of cognitive abilities, severe neurodegeneration, synaptic loss and mitochondrial dysfunction. The Wnt signaling pathway participates in the development of the central ne...
Autores principales: | Silva-Alvarez, Carmen, Arrázola, Macarena S., Godoy, Juan A., Ordenes, Daniela, Inestrosa, Nibaldo C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691552/ https://www.ncbi.nlm.nih.gov/pubmed/23805073 http://dx.doi.org/10.3389/fncel.2013.00097 |
Ejemplares similares
-
Wnt Signaling Prevents the Aβ Oligomer-Induced Mitochondrial Permeability Transition Pore Opening Preserving Mitochondrial Structure in Hippocampal Neurons
por: Arrázola, Macarena S., et al.
Publicado: (2017) -
How the Wnt signaling pathway protects from neurodegeneration: the mitochondrial scenario
por: Arrázola, Macarena S., et al.
Publicado: (2015) -
Wnt Signaling Upregulates Teneurin-3 Expression via Canonical and Non-canonical Wnt Pathway Crosstalk
por: Bastías-Candia, Sussy, et al.
Publicado: (2019) -
Loss of canonical Wnt signaling is involved in the pathogenesis of Alzheimer's disease
por: Tapia-Rojas, Cheril, et al.
Publicado: (2018) -
Wnt-5a occludes Aβ oligomer-induced depression of glutamatergic transmission in hippocampal neurons
por: Cerpa, Waldo, et al.
Publicado: (2010)