Methylation kinetics and CpG-island methylator phenotyope status in colorectal cancer cell lines

BACKGROUND: Hypermethylation of CpG islands is thought to contribute to carcinogenesis through the inactivation of tumor suppressor genes. Tumor cells with relatively high levels of CpG island methylation are considered CpG island methylator phenotypes (CIMP). The mechanisms that are responsible for...

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Detalles Bibliográficos
Autores principales: Wodarz, Dominik, Boland, C Richard, Goel, Ajay, Komarova, Natalia L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691599/
https://www.ncbi.nlm.nih.gov/pubmed/23758948
http://dx.doi.org/10.1186/1745-6150-8-14

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