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Impact of anti-CD25 monoclonal antibody on dendritic cell-tumor fusion vaccine efficacy in a murine melanoma model

BACKGROUND: A promising cancer vaccine involves the fusion of tumor cells with dendritic cells (DCs). As such, a broad spectrum of both known and unidentified tumor antigens is presented to the immune system in the context of the potent immunostimulatory capacity of DCs. Murine studies have demonstr...

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Detalles Bibliográficos
Autores principales: Tan, Chunrui, Reddy, Varun, Dannull, Jens, Ding, Enyu, Nair, Smita K, Tyler, Douglas S, Pruitt, Scott K, Lee, Walter T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691646/
https://www.ncbi.nlm.nih.gov/pubmed/23768240
http://dx.doi.org/10.1186/1479-5876-11-148