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High-throughput sequencing of cytosine methylation in plant DNA
Cytosine methylation is a significant and widespread regulatory factor in plant systems. Methods for the high-throughput sequencing of methylation have allowed a greatly improved characterisation of the methylome. Here we discuss currently available methods for generation and analysis of high-throug...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691832/ https://www.ncbi.nlm.nih.gov/pubmed/23758782 http://dx.doi.org/10.1186/1746-4811-9-16 |
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| author | Hardcastle, Thomas J |
| author_facet | Hardcastle, Thomas J |
| author_sort | Hardcastle, Thomas J |
| collection | PubMed |
| description | Cytosine methylation is a significant and widespread regulatory factor in plant systems. Methods for the high-throughput sequencing of methylation have allowed a greatly improved characterisation of the methylome. Here we discuss currently available methods for generation and analysis of high-throughput sequencing of methylation data. We also discuss the results previously acquired through sequencing plant methylomes, and highlight remaining challenges in this field. |
| format | Online Article Text |
| id | pubmed-3691832 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2013 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-36918322013-06-26 High-throughput sequencing of cytosine methylation in plant DNA Hardcastle, Thomas J Plant Methods Review Cytosine methylation is a significant and widespread regulatory factor in plant systems. Methods for the high-throughput sequencing of methylation have allowed a greatly improved characterisation of the methylome. Here we discuss currently available methods for generation and analysis of high-throughput sequencing of methylation data. We also discuss the results previously acquired through sequencing plant methylomes, and highlight remaining challenges in this field. BioMed Central 2013-06-07 /pmc/articles/PMC3691832/ /pubmed/23758782 http://dx.doi.org/10.1186/1746-4811-9-16 Text en Copyright © 2013 Hardcastle; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Review Hardcastle, Thomas J High-throughput sequencing of cytosine methylation in plant DNA |
| title | High-throughput sequencing of cytosine methylation in plant DNA |
| title_full | High-throughput sequencing of cytosine methylation in plant DNA |
| title_fullStr | High-throughput sequencing of cytosine methylation in plant DNA |
| title_full_unstemmed | High-throughput sequencing of cytosine methylation in plant DNA |
| title_short | High-throughput sequencing of cytosine methylation in plant DNA |
| title_sort | high-throughput sequencing of cytosine methylation in plant dna |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691832/ https://www.ncbi.nlm.nih.gov/pubmed/23758782 http://dx.doi.org/10.1186/1746-4811-9-16 |
| work_keys_str_mv | AT hardcastlethomasj highthroughputsequencingofcytosinemethylationinplantdna |